2c51: Difference between revisions
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<StructureSection load='2c51' size='340' side='right'caption='[[2c51]], [[Resolution|resolution]] 2.80Å' scene=''> | <StructureSection load='2c51' size='340' side='right'caption='[[2c51]], [[Resolution|resolution]] 2.80Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[2c51]] is a 5 chain structure with sequence from [ | <table><tr><td colspan='2'>[[2c51]] is a 5 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_phage_MS2 Escherichia phage MS2]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=1h8j 1h8j]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2C51 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2C51 FirstGlance]. <br> | ||
</td></tr><tr id=' | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.8Å</td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2c51 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2c51 OCA], [https://pdbe.org/2c51 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2c51 RCSB], [https://www.ebi.ac.uk/pdbsum/2c51 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2c51 ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
[ | [https://www.uniprot.org/uniprot/CAPSD_BPMS2 CAPSD_BPMS2] Self-assembles to form the T=3 icosahedral virus shell that protects the viral nucleic acid. Acts as a translational repressor by binding with high specificity to a single stem-loop structure in the genomic RNA that contains the initiation codon of the gene for the viral replicase. Involved in virus assembly through the interaction between a capsid protein dimer and the multiple packaging signals present in the RNA genome.<ref>PMID:16531233</ref> <ref>PMID:18662904</ref> <ref>PMID:26608810</ref> <ref>PMID:8254664</ref> <ref>PMID:9245600</ref> <ref>PMID:9469847</ref> | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: | [[Category: Escherichia phage MS2]] | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: Davis | [[Category: Davis DR]] | ||
[[Category: Fridborg | [[Category: Fridborg K]] | ||
[[Category: Grahn | [[Category: Grahn E]] | ||
[[Category: Helgstrand | [[Category: Helgstrand C]] | ||
[[Category: Lago | [[Category: Lago H]] | ||
[[Category: Liljas | [[Category: Liljas L]] | ||
[[Category: Moss | [[Category: Moss T]] | ||
[[Category: Stockley | [[Category: Stockley PG]] | ||
[[Category: Stonehouse | [[Category: Stonehouse NJ]] | ||
[[Category: Sundaram | [[Category: Sundaram M]] | ||
[[Category: Tars | [[Category: Tars K]] | ||