2c27: Difference between revisions
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==The | ==The Structure of Mycothiol Synthase in Complex with des- AcetylMycothiol and CoenzymeA.== | ||
<StructureSection load='2c27' size='340' side='right' caption='[[2c27]], [[Resolution|resolution]] 1.80Å' scene=''> | <StructureSection load='2c27' size='340' side='right'caption='[[2c27]], [[Resolution|resolution]] 1.80Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[2c27]] is a 1 chain structure with sequence from [ | <table><tr><td colspan='2'>[[2c27]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis_H37Rv Mycobacterium tuberculosis H37Rv]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2C27 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2C27 FirstGlance]. <br> | ||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACO:ACETYL+COENZYME+*A'>ACO</scene>, <scene name='pdbligand=COA:COENZYME+A'>COA</scene>, <scene name='pdbligand=MA8:(2S,3R,5S,6S)-2,3,4,5,6-PENTAHYDROXYCYCLOHEXYL+2-(L-CYSTEINYLAMINO)-2-DEOXY-ALPHA-L-GLUCOPYRANOSIDE'>MA8</scene> | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8Å</td></tr> | ||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACO:ACETYL+COENZYME+*A'>ACO</scene>, <scene name='pdbligand=COA:COENZYME+A'>COA</scene>, <scene name='pdbligand=MA8:(2S,3R,5S,6S)-2,3,4,5,6-PENTAHYDROXYCYCLOHEXYL+2-(L-CYSTEINYLAMINO)-2-DEOXY-ALPHA-L-GLUCOPYRANOSIDE'>MA8</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2c27 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2c27 OCA], [https://pdbe.org/2c27 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2c27 RCSB], [https://www.ebi.ac.uk/pdbsum/2c27 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2c27 ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
[ | [https://www.uniprot.org/uniprot/MSHD_MYCTU MSHD_MYCTU] Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol.<ref>PMID:12375100</ref> | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: | [[Category: Large Structures]] | ||
[[Category: | [[Category: Mycobacterium tuberculosis H37Rv]] | ||
[[Category: | [[Category: Blanchard JS]] | ||
[[Category: | [[Category: Rendle PM]] | ||
[[Category: | [[Category: Vetting MW]] | ||
[[Category: | [[Category: Yu M]] | ||