2bv1: Difference between revisions
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== | |||
<StructureSection load='2bv1' size='340' side='right' caption='[[2bv1]], [[Resolution|resolution]] 2.00Å' scene=''> | ==Regulator of G-protein Signalling 1 (Human)== | ||
<StructureSection load='2bv1' size='340' side='right'caption='[[2bv1]], [[Resolution|resolution]] 2.00Å' scene=''> | |||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[2bv1]] is a 2 chain structure with sequence from [ | <table><tr><td colspan='2'>[[2bv1]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2BV1 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2BV1 FirstGlance]. <br> | ||
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2Å</td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2bv1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2bv1 OCA], [https://pdbe.org/2bv1 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2bv1 RCSB], [https://www.ebi.ac.uk/pdbsum/2bv1 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2bv1 ProSAT]</span></td></tr> | |||
</table> | </table> | ||
== Function == | |||
[https://www.uniprot.org/uniprot/RGS1_HUMAN RGS1_HUMAN] Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. This protein may be involved in the regulation of B-cell activation and proliferation. | |||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
Check<jmol> | Check<jmol> | ||
<jmolCheckbox> | <jmolCheckbox> | ||
<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/bv/2bv1_consurf.spt"</scriptWhenChecked> | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/bv/2bv1_consurf.spt"</scriptWhenChecked> | ||
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
<text>to colour the structure by Evolutionary Conservation</text> | <text>to colour the structure by Evolutionary Conservation</text> | ||
</jmolCheckbox> | </jmolCheckbox> | ||
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/ | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2bv1 ConSurf]. | ||
<div style="clear:both"></div> | <div style="clear:both"></div> | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
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</div> | </div> | ||
<div class="pdbe-citations 2bv1" style="background-color:#fffaf0;"></div> | <div class="pdbe-citations 2bv1" style="background-color:#fffaf0;"></div> | ||
==See Also== | |||
*[[Regulator of G-protein signaling 3D structures|Regulator of G-protein signaling 3D structures]] | |||
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: | [[Category: Homo sapiens]] | ||
[[Category: Arrowsmith | [[Category: Large Structures]] | ||
[[Category: Doyle | [[Category: Arrowsmith C]] | ||
[[Category: Edwards | [[Category: Doyle DA]] | ||
[[Category: Elkins | [[Category: Edwards A]] | ||
[[Category: Haroniti | [[Category: Elkins JM]] | ||
[[Category: Schoch | [[Category: Haroniti A]] | ||
[[Category: Soundararajan | [[Category: Schoch GA]] | ||
[[Category: Sundstrom | [[Category: Soundararajan M]] | ||
[[Category: Yang | [[Category: Sundstrom M]] | ||
[[Category: Yang X]] | |||