2bgq: Difference between revisions

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[[Image:2bgq.gif|left|200px]]<br />
<applet load="2bgq" size="450" color="white" frame="true" align="right" spinBox="true"
caption="2bgq, resolution 2.50&Aring;" />
'''APO ALDOSE REDUCTASE FROM BARLEY'''<br />


==About this Structure==
==apo aldose reductase from barley==
2BGQ is a [[http://en.wikipedia.org/wiki/Single_protein Single protein]] structure of sequence from [[http://en.wikipedia.org/wiki/Hordeum_vulgare Hordeum vulgare]] with SO4 as [[http://en.wikipedia.org/wiki/ligand ligand]]. Active as [[http://en.wikipedia.org/wiki/Aldehyde_reductase Aldehyde reductase]], with EC number [[http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.1.21 1.1.1.21]]. Structure known Active Site: AC1. Full crystallographic information is available from [[http://ispc.weizmann.ac.il/oca-bin/ocashort?id=2BGQ OCA]].  
<StructureSection load='2bgq' size='340' side='right'caption='[[2bgq]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
[[Category: Aldehyde reductase]]
== Structural highlights ==
<table><tr><td colspan='2'>[[2bgq]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Hordeum_vulgare Hordeum vulgare]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2BGQ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2BGQ FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.5&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2bgq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2bgq OCA], [https://pdbe.org/2bgq PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2bgq RCSB], [https://www.ebi.ac.uk/pdbsum/2bgq PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2bgq ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/ALDR_HORVU ALDR_HORVU]
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/bg/2bgq_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2bgq ConSurf].
<div style="clear:both"></div>
 
==See Also==
*[[Aldose reductase 3D structures|Aldose reductase 3D structures]]
__TOC__
</StructureSection>
[[Category: Hordeum vulgare]]
[[Category: Hordeum vulgare]]
[[Category: Single protein]]
[[Category: Large Structures]]
[[Category: Christensen, C.L.]]
[[Category: Christensen CL]]
[[Category: Henriksen, A.]]
[[Category: Henriksen A]]
[[Category: Olsen, J.G.]]
[[Category: Olsen JG]]
[[Category: Olsen, O.]]
[[Category: Olsen O]]
[[Category: Pedersen, L.]]
[[Category: Pedersen L]]
[[Category: SO4]]
[[Category: aldo/keto reductase oxidoreductase]]
[[Category: aldose reductase]]
[[Category: apoenzyme]]
 
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