1w9o: Difference between revisions

← Older edit

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

OCA

@@ Line 3: / Line 3: @@
 <StructureSection load='1w9o' size='340' side='right'caption='[[1w9o]], [[Resolution|resolution]] 2.25&Aring;' scene=''>
 == Structural highlights ==
-<table><tr><td colspan='2'>[[1w9o]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1W9O OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=1W9O FirstGlance]. <br>
+<table><tr><td colspan='2'>[[1w9o]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1W9O OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1W9O FirstGlance]. <br>
-</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BEZ:BENZOIC+ACID'>BEZ</scene></td></tr>
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.25&#8491;</td></tr>
-<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1n99|1n99]], [[1nte|1nte]], [[1obx|1obx]], [[1oby|1oby]], [[1obz|1obz]], [[1r6j|1r6j]], [[1v1t|1v1t]], [[1w9e|1w9e]], [[1w9q|1w9q]], [[1ybo|1ybo]]</div></td></tr>
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BEZ:BENZOIC+ACID'>BEZ</scene></td></tr>
-<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">SDCBP, MDA9, SYCL ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1w9o FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1w9o OCA], [https://pdbe.org/1w9o PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1w9o RCSB], [https://www.ebi.ac.uk/pdbsum/1w9o PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1w9o ProSAT]</span></td></tr>
-<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=1w9o FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1w9o OCA], [http://pdbe.org/1w9o PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1w9o RCSB], [http://www.ebi.ac.uk/pdbsum/1w9o PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1w9o ProSAT]</span></td></tr>
 </table>
+== Function ==
+[https://www.uniprot.org/uniprot/SDCB1_HUMAN SDCB1_HUMAN] Seems to function as an adapter protein. In adherens junctions may function to couple syndecans to cytoskeletal proteins or signaling components. Seems to couple transcription factor SOX4 to the IL-5 receptor (IL5RA). May also play a role in vesicular trafficking. Seems to be required for the targeting of TGFA to the cell surface in the early secretory pathway.<ref>PMID:10230395</ref> <ref>PMID:11179419</ref> <ref>PMID:11498591</ref>
 == Evolutionary Conservation ==
 [[Image:Consurf_key_small.gif|200px|right]]
@@ Line 28: / Line 29: @@
 </div>
 <div class="pdbe-citations 1w9o" style="background-color:#fffaf0;"></div>
+==See Also==
+*[[3D structures of syntenin|3D structures of syntenin]]
 == References ==
 <references/>
 __TOC__
 </StructureSection>
-[[Category: Human]]
+[[Category: Homo sapiens]]
 [[Category: Large Structures]]
-[[Category: Cierpicki, T]]
+[[Category: Synthetic construct]]
-[[Category: Cooper, D R]]
+[[Category: Cierpicki T]]
-[[Category: Derewenda, U]]
+[[Category: Cooper DR]]
-[[Category: Derewenda, Z S]]
+[[Category: Derewenda U]]
-[[Category: Devedjiev, Y]]
+[[Category: Derewenda ZS]]
-[[Category: Grembecka, J]]
+[[Category: Devedjiev Y]]
-[[Category: Adhesion-complex]]
+[[Category: Grembecka J]]
-[[Category: Cell adhesion]]
-[[Category: Pdz domain]]
-[[Category: Scaffolding protein]]