1w9j: Difference between revisions

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[[Image:1w9j.gif|left|200px]]<br /><applet load="1w9j" size="350" color="white" frame="true" align="right" spinBox="true"
caption="1w9j, resolution 2.00&Aring;" />
'''MYOSIN II DICTYOSTELIUM DISCOIDEUM MOTOR DOMAIN S456Y BOUND WITH MGADP-ALF4'''<br />


==About this Structure==
==Myosin II Dictyostelium discoideum motor domain S456Y bound with MgADP-AlF4==
1W9J is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Dictyostelium_discoideum Dictyostelium discoideum] with <scene name='pdbligand=MG:'>MG</scene>, <scene name='pdbligand=ALF:'>ALF</scene>, <scene name='pdbligand=ADP:'>ADP</scene> and <scene name='pdbligand=EDO:'>EDO</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Myosin_ATPase Myosin ATPase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.6.4.1 3.6.4.1] Known structural/functional Site: <scene name='pdbsite=AC1:Edo+Binding+Site+For+Chain+A'>AC1</scene>. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1W9J OCA].  
<StructureSection load='1w9j' size='340' side='right'caption='[[1w9j]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[1w9j]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Dictyostelium_discoideum Dictyostelium discoideum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1W9J OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1W9J FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=ALF:TETRAFLUOROALUMINATE+ION'>ALF</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1w9j FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1w9j OCA], [https://pdbe.org/1w9j PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1w9j RCSB], [https://www.ebi.ac.uk/pdbsum/1w9j PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1w9j ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/MYS2_DICDI MYS2_DICDI] Myosin is a protein that binds to actin and has ATPase activity that is activated by actin.
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/w9/1w9j_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1w9j ConSurf].
<div style="clear:both"></div>
 
==See Also==
*[[Myosin 3D Structures|Myosin 3D Structures]]
__TOC__
</StructureSection>
[[Category: Dictyostelium discoideum]]
[[Category: Dictyostelium discoideum]]
[[Category: Myosin ATPase]]
[[Category: Large Structures]]
[[Category: Single protein]]
[[Category: Coureux P-D]]
[[Category: Coureux, P.D.]]
[[Category: Houdusse A]]
[[Category: Houdusse, A.]]
[[Category: Morris CA]]
[[Category: Morris, C.A.]]
[[Category: Sweeney HL]]
[[Category: Sweeney, H.L.]]
[[Category: Wells AL]]
[[Category: Wells, A.L.]]
[[Category: ADP]]
[[Category: ALF]]
[[Category: EDO]]
[[Category: MG]]
[[Category: atpase]]
[[Category: molecular motor]]
[[Category: motor domain]]
[[Category: muscle contraction]]
[[Category: mutant]]
[[Category: myosin]]
 
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