1w6g: Difference between revisions

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-[[Image:1w6g.png|left|200px]]
-<!--
+==AGAO holoenzyme at 1.55 angstroms==
-The line below this paragraph, containing "STRUCTURE_1w6g", creates the "Structure Box" on the page.
+<StructureSection load='1w6g' size='340' side='right'caption='[[1w6g]], [[Resolution|resolution]] 1.55&Aring;' scene=''>
-You may change the PDB parameter (which sets the PDB file loaded into the applet)
+== Structural highlights ==
-or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+<table><tr><td colspan='2'>[[1w6g]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Arthrobacter_globiformis Arthrobacter globiformis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1W6G OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1W6G FirstGlance]. <br>
-or leave the SCENE parameter empty for the default display.
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.55&#8491;</td></tr>
--->
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CU:COPPER+(II)+ION'>CU</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=TPQ:5-(2-CARBOXY-2-AMINOETHYL)-2-HYDROXY-1,4-BENZOQUINONE'>TPQ</scene></td></tr>
-{{STRUCTURE_1w6g|  PDB=1w6g  |  SCENE=  }}
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1w6g FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1w6g OCA], [https://pdbe.org/1w6g PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1w6g RCSB], [https://www.ebi.ac.uk/pdbsum/1w6g PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1w6g ProSAT]</span></td></tr>
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/PAOX_ARTGO PAOX_ARTGO]
+== Evolutionary Conservation ==
+[[Image:Consurf_key_small.gif|200px|right]]
+Check<jmol>
+  <jmolCheckbox>
+    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/w6/1w6g_consurf.spt"</scriptWhenChecked>
+    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
+    <text>to colour the structure by Evolutionary Conservation</text>
+  </jmolCheckbox>
+</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1w6g ConSurf].
+<div style="clear:both"></div>
+<div style="background-color:#fffaf0;">
+== Publication Abstract from PubMed ==
+Copper-containing amine oxidases are found in all the major kingdoms of life. They catalyse the oxidation of organic amines in the presence of molecular dioxygen to aldehydes and hydrogen peroxide. The catalytic centres contain a Cu atom and a topaquinone cofactor formed autocatalytically from a tyrosine residue in the presence of Cu and molecular oxygen. The structure of the Cu-containing amine oxidase from Arthrobacter globiformis, which was previously refined at 1.8 A resolution in space group C2 with unit-cell parameters a = 157.84, b = 63.24, c = 91.98 A, beta = 112.0 degrees [Wilce et al. (1997), Biochemistry, 36, 16116-16133], has been re-refined with newly recorded data at 1.55 A resolution. The structure has also been solved and refined at 2.2 A resolution in a new crystal form, space group C2, with unit-cell parameters a = 158.04, b = 64.06, c = 69.69 A, beta = 111.7 degrees.
-===AGAO HOLOENZYME AT 1.55 ANGSTROMS===
+The copper-containing amine oxidase from Arthrobacter globiformis: refinement at 1.55 and 2.20 A resolution in two crystal forms.,Langley DB, Duff AP, Freeman HC, Guss JM Acta Crystallogr Sect F Struct Biol Cryst Commun. 2006 Nov 1;62(Pt, 11):1052-7. Epub 2006 Oct 25. PMID:17077478<ref>PMID:17077478</ref>
+From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
+</div>
+<div class="pdbe-citations 1w6g" style="background-color:#fffaf0;"></div>
-<!--
+==See Also==
-The line below this paragraph, {{ABSTRACT_PUBMED_17077478}}, adds the Publication Abstract to the page
+*[[Copper amine oxidase 3D structures|Copper amine oxidase 3D structures]]
-(as it appears on PubMed at http://www.pubmed.gov), where 17077478 is the PubMed ID number.
+== References ==
--->
+<references/>
-{{ABSTRACT_PUBMED_17077478}}
+__TOC__
+</StructureSection>
-==About this Structure==
-[[1w6g]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Arthrobacter_globiformis Arthrobacter globiformis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1W6G OCA].
-==Reference==
-<ref group="xtra">PMID:17077478</ref><ref group="xtra">PMID:11483008</ref><references group="xtra"/>
 [[Category: Arthrobacter globiformis]]
-[[Category: Oxidoreductase]]
+[[Category: Large Structures]]
-[[Category: Dooley, D M.]]
+[[Category: Dooley DM]]
-[[Category: Duff, A P.]]
+[[Category: Duff AP]]
-[[Category: Freeman, H C.]]
+[[Category: Freeman HC]]
-[[Category: Guss, J M.]]
+[[Category: Guss JM]]
-[[Category: Juda, G A.]]
+[[Category: Juda GA]]
-[[Category: Langley, D B.]]
+[[Category: Langley DB]]
-[[Category: Shepard, E M.]]
+[[Category: Shepard EM]]
-[[Category: 3d-structure]]
-[[Category: Amine oxidase]]
-[[Category: Arthrobacter globiformi]]
-[[Category: Copper]]
-[[Category: Copper containing]]
-[[Category: Holoenzyme]]
-[[Category: Metal-binding]]
-[[Category: Oxidoreductase]]
-[[Category: Quinone]]
-[[Category: Tpq]]