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==Crystal structure of an artificial top component of turnip yellow mosaic virus== | |||
<StructureSection load='1w39' size='340' side='right'caption='[[1w39]], [[Resolution|resolution]] 3.75Å' scene=''> | |||
| | == Structural highlights == | ||
| | <table><tr><td colspan='2'>[[1w39]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Turnip_yellow_mosaic_virus Turnip yellow mosaic virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1W39 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1W39 FirstGlance]. <br> | ||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.75Å</td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1w39 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1w39 OCA], [https://pdbe.org/1w39 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1w39 RCSB], [https://www.ebi.ac.uk/pdbsum/1w39 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1w39 ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/COAT_TYMV COAT_TYMV] | |||
== Evolutionary Conservation == | |||
[[Image:Consurf_key_small.gif|200px|right]] | |||
Check<jmol> | |||
<jmolCheckbox> | |||
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/w3/1w39_consurf.spt"</scriptWhenChecked> | |||
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | |||
<text>to colour the structure by Evolutionary Conservation</text> | |||
</jmolCheckbox> | |||
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1w39 ConSurf]. | |||
<div style="clear:both"></div> | |||
<div style="background-color:#fffaf0;"> | |||
== Publication Abstract from PubMed == | |||
Empty capsids (artificial top component) of turnip yellow mosaic virus were co-crystallized with an encapsidation initiator RNA hairpin. No clear density was observed for the RNA, but there were clear differences in the conformation of a loop of the coat protein at the opening of the pentameric capsomer (formed by five A-subunits) protruding from the capsid, compared to the corresponding loop in the intact virus. Further differences were found at the N terminus of the A-subunit. These differences have implications for the mechanism of decapsidation of the virus, required for infection. | |||
Crystal structure of an empty capsid of turnip yellow mosaic virus.,van Roon AM, Bink HH, Plaisier JR, Pleij CW, Abrahams JP, Pannu NS J Mol Biol. 2004 Aug 27;341(5):1205-14. PMID:15321716<ref>PMID:15321716</ref> | |||
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | |||
</div> | |||
<div class="pdbe-citations 1w39" style="background-color:#fffaf0;"></div> | |||
== | ==See Also== | ||
*[[Virus coat proteins 3D structures|Virus coat proteins 3D structures]] | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
== | [[Category: Large Structures]] | ||
[[Category: | |||
[[Category: Turnip yellow mosaic virus]] | [[Category: Turnip yellow mosaic virus]] | ||
[[Category: Abrahams | [[Category: Abrahams JP]] | ||
[[Category: Bink | [[Category: Bink HHJ]] | ||
[[Category: Pannu | [[Category: Pannu NS]] | ||
[[Category: Plaisier | [[Category: Plaisier JR]] | ||
[[Category: Pleij | [[Category: Pleij CWA]] | ||
[[Category: Roon | [[Category: Van Roon AMM]] | ||
Latest revision as of 16:14, 13 December 2023
Crystal structure of an artificial top component of turnip yellow mosaic virusCrystal structure of an artificial top component of turnip yellow mosaic virus
Structural highlights
FunctionEvolutionary Conservation Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf. Publication Abstract from PubMedEmpty capsids (artificial top component) of turnip yellow mosaic virus were co-crystallized with an encapsidation initiator RNA hairpin. No clear density was observed for the RNA, but there were clear differences in the conformation of a loop of the coat protein at the opening of the pentameric capsomer (formed by five A-subunits) protruding from the capsid, compared to the corresponding loop in the intact virus. Further differences were found at the N terminus of the A-subunit. These differences have implications for the mechanism of decapsidation of the virus, required for infection. Crystal structure of an empty capsid of turnip yellow mosaic virus.,van Roon AM, Bink HH, Plaisier JR, Pleij CW, Abrahams JP, Pannu NS J Mol Biol. 2004 Aug 27;341(5):1205-14. PMID:15321716[1] From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine. See AlsoReferences
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