1of6: Difference between revisions

← Older edit

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

OCA

@@ Line 1: / Line 1: @@
-[[Image:1of6.png|left|200px]]
-{{STRUCTURE_1of6|  PDB=1of6  |  SCENE=  }}
+==crystal structure of the tyrosine-regulated 3-deoxy-d-arabino-heptulosonate-7-phosphate synthase from saccharomyces cerevisiae complexed with tyrosine and manganese==
+<StructureSection load='1of6' size='340' side='right'caption='[[1of6]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
-===CRYSTAL STRUCTURE OF THE TYROSINE-REGULATED 3-DEOXY-D-ARABINO-HEPTULOSONATE-7-PHOSPHATE SYNTHASE FROM SACCHAROMYCES CEREVISIAE COMPLEXED WITH TYROSINE AND MANGANESE===
+== Structural highlights ==
+<table><tr><td colspan='2'>[[1of6]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1OF6 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1OF6 FirstGlance]. <br>
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.1&#8491;</td></tr>
-==About this Structure==
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=DTY:D-TYROSINE'>DTY</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene></td></tr>
-[[1of6]] is a 8 chain structure of [[Aldolase]] with sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1OF6 OCA].
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1of6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1of6 OCA], [https://pdbe.org/1of6 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1of6 RCSB], [https://www.ebi.ac.uk/pdbsum/1of6 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1of6 ProSAT]</span></td></tr>
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/AROG_YEAST AROG_YEAST] Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP).
+== Evolutionary Conservation ==
+[[Image:Consurf_key_small.gif|200px|right]]
+Check<jmol>
+  <jmolCheckbox>
+    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/of/1of6_consurf.spt"</scriptWhenChecked>
+    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
+    <text>to colour the structure by Evolutionary Conservation</text>
+  </jmolCheckbox>
+</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1of6 ConSurf].
+<div style="clear:both"></div>
 ==See Also==
-*[[Aldolase|Aldolase]]
+*[[DAHP synthase 3D structures|DAHP synthase 3D structures]]
-[[Category: 3-deoxy-7-phosphoheptulonate synthase]]
+__TOC__
+</StructureSection>
+[[Category: Large Structures]]
 [[Category: Saccharomyces cerevisiae]]
-[[Category: Braus, G.]]
+[[Category: Braus G]]
-[[Category: Heinrich, G.]]
+[[Category: Heinrich G]]
-[[Category: Koenig, V.]]
+[[Category: Koenig V]]
-[[Category: Pfeil, A.]]
+[[Category: Pfeil A]]
-[[Category: Schneider, T R.]]
+[[Category: Schneider TR]]
-[[Category: Aldolase]]
-[[Category: Beta-alpha-barrel]]
-[[Category: Lyase]]
-[[Category: Synthase]]
-[[Category: Synthetase]]