1oe9: Difference between revisions

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==CRYSTAL STRUCTURE OF MYOSIN V MOTOR WITH ESSENTIAL LIGHT CHAIN - NUCLEOTIDE-FREE==
 
<StructureSection load='1oe9' size='340' side='right' caption='[[1oe9]], [[Resolution|resolution]] 2.05&Aring;' scene=''>
==Crystal structure of Myosin V motor with essential light chain-nucleotide-free==
<StructureSection load='1oe9' size='340' side='right'caption='[[1oe9]], [[Resolution|resolution]] 2.05&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[1oe9]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Chick Chick] and [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1OE9 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1OE9 FirstGlance]. <br>
<table><tr><td colspan='2'>[[1oe9]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus] and [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1OE9 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1OE9 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.05&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1oe9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1oe9 OCA], [http://pdbe.org/1oe9 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1oe9 RCSB], [http://www.ebi.ac.uk/pdbsum/1oe9 PDBsum]</span></td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1oe9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1oe9 OCA], [https://pdbe.org/1oe9 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1oe9 RCSB], [https://www.ebi.ac.uk/pdbsum/1oe9 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1oe9 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/MYO5A_CHICK MYO5A_CHICK]] Processive actin-based motor that can move in large steps approximating the 36-nm pseudo-repeat of the actin filament. Involved in melanosome transport. Also mediates the transport of vesicles to the plasma membrane. May also be required for some polarization process involved in dendrite formation (By similarity). [[http://www.uniprot.org/uniprot/MYL6B_HUMAN MYL6B_HUMAN]] Regulatory light chain of myosin. Does not bind calcium.  
[https://www.uniprot.org/uniprot/MYO5A_CHICK MYO5A_CHICK] Processive actin-based motor that can move in large steps approximating the 36-nm pseudo-repeat of the actin filament. Involved in melanosome transport. Also mediates the transport of vesicles to the plasma membrane. May also be required for some polarization process involved in dendrite formation (By similarity).
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
   <jmolCheckbox>
   <jmolCheckbox>
     <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/oe/1oe9_consurf.spt"</scriptWhenChecked>
     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/oe/1oe9_consurf.spt"</scriptWhenChecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <text>to colour the structure by Evolutionary Conservation</text>
     <text>to colour the structure by Evolutionary Conservation</text>
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==See Also==
==See Also==
*[[Myosin|Myosin]]
*[[Myosin 3D Structures|Myosin 3D Structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Chick]]
[[Category: Gallus gallus]]
[[Category: Human]]
[[Category: Homo sapiens]]
[[Category: Coureux, P D]]
[[Category: Large Structures]]
[[Category: Houdusse, A]]
[[Category: Coureux P-D]]
[[Category: Menetrey, J]]
[[Category: Houdusse A]]
[[Category: Morris, C A]]
[[Category: Menetrey J]]
[[Category: Sweeney, H L]]
[[Category: Morris CA]]
[[Category: Wells, A L]]
[[Category: Sweeney HL]]
[[Category: Yengo, C M]]
[[Category: Wells AL]]
[[Category: Atp-binding]]
[[Category: Yengo CM]]
[[Category: Atpase]]
[[Category: Atpase-myosin complex]]
[[Category: Atpase/myosin]]
[[Category: Chicken]]
[[Category: Elc]]
[[Category: Iq motif]]
[[Category: Molecular motor]]
[[Category: Muscle protein]]
[[Category: Myosin v]]
[[Category: Unconventional myosin]]

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