1hk9: Difference between revisions

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 ==Crystal structure of the Hfq protein from Escherichia coli==
-<StructureSection load='1hk9' size='340' side='right' caption='[[1hk9]], [[Resolution|resolution]] 2.15&Aring;' scene=''>
+<StructureSection load='1hk9' size='340' side='right'caption='[[1hk9]], [[Resolution|resolution]] 2.15&Aring;' scene=''>
 == Structural highlights ==
-<table><tr><td colspan='2'>[[1hk9]] is a 6 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1HK9 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1HK9 FirstGlance]. <br>
+<table><tr><td colspan='2'>[[1hk9]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1HK9 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1HK9 FirstGlance]. <br>
-</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1hk9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1hk9 OCA], [http://pdbe.org/1hk9 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1hk9 RCSB], [http://www.ebi.ac.uk/pdbsum/1hk9 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1hk9 ProSAT]</span></td></tr>
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.15&#8491;</td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1hk9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1hk9 OCA], [https://pdbe.org/1hk9 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1hk9 RCSB], [https://www.ebi.ac.uk/pdbsum/1hk9 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1hk9 ProSAT]</span></td></tr>
 </table>
 == Function ==
-[[http://www.uniprot.org/uniprot/HFQ_ECOLI HFQ_ECOLI]] RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Involved in the regulation of stress responses mediated by the sigma factors RpoS, sigma-E and sigma-32. Binds with high specificity to tRNAs. In vitro, stimulates synthesis of long tails by poly(A) polymerase I. Required for RNA phage Qbeta replication.<ref>PMID:805130</ref> <ref>PMID:10677490</ref> <ref>PMID:11222598</ref> <ref>PMID:17158661</ref> <ref>PMID:19909729</ref>   Seems to play a role in persister cell formation; upon overexpression decreases persister cell formation while deletion increases persister formation.<ref>PMID:805130</ref> <ref>PMID:10677490</ref> <ref>PMID:11222598</ref> <ref>PMID:17158661</ref> <ref>PMID:19909729</ref>
+[https://www.uniprot.org/uniprot/HFQ_ECOLI HFQ_ECOLI] RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Involved in the regulation of stress responses mediated by the sigma factors RpoS, sigma-E and sigma-32. Binds with high specificity to tRNAs. In vitro, stimulates synthesis of long tails by poly(A) polymerase I. Required for RNA phage Qbeta replication.<ref>PMID:805130</ref> <ref>PMID:10677490</ref> <ref>PMID:11222598</ref> <ref>PMID:17158661</ref> <ref>PMID:19909729</ref>   Seems to play a role in persister cell formation; upon overexpression decreases persister cell formation while deletion increases persister formation.<ref>PMID:805130</ref> <ref>PMID:10677490</ref> <ref>PMID:11222598</ref> <ref>PMID:17158661</ref> <ref>PMID:19909729</ref>
 == Evolutionary Conservation ==
 [[Image:Consurf_key_small.gif|200px|right]]
 Check<jmol>
    <jmolCheckbox>
-     <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/hk/1hk9_consurf.spt"</scriptWhenChecked>
+     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/hk/1hk9_consurf.spt"</scriptWhenChecked>
      <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
      <text>to colour the structure by Evolutionary Conservation</text>
@@ Line 27: / Line 28: @@
 </div>
 <div class="pdbe-citations 1hk9" style="background-color:#fffaf0;"></div>
+==See Also==
+*[[Protein Hfq 3D structures|Protein Hfq 3D structures]]
 == References ==
 <references/>
 __TOC__
 </StructureSection>
-[[Category: Basquin, J]]
+[[Category: Escherichia coli]]
-[[Category: Sauter, C]]
+[[Category: Large Structures]]
-[[Category: Suck, D]]
+[[Category: Basquin J]]
-[[Category: Pleiotropic regulator]]
+[[Category: Sauter C]]
-[[Category: Rna binding protein]]
+[[Category: Suck D]]
-[[Category: Rna chaperone]]
-[[Category: Rna-binding protein]]
-[[Category: Sm-like]]