1hb6: Difference between revisions
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==Structure of bovine Acyl-CoA binding protein in orthorhombic crystal form== | ==Structure of bovine Acyl-CoA binding protein in orthorhombic crystal form== | ||
<StructureSection load='1hb6' size='340' side='right' caption='[[1hb6]], [[Resolution|resolution]] 2.00Å' scene=''> | <StructureSection load='1hb6' size='340' side='right'caption='[[1hb6]], [[Resolution|resolution]] 2.00Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[1hb6]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1HB6 OCA]. For a <b>guided tour on the structure components</b> use [ | <table><tr><td colspan='2'>[[1hb6]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1HB6 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1HB6 FirstGlance]. <br> | ||
</td></tr><tr id=' | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2Å</td></tr> | ||
<tr id=' | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CD:CADMIUM+ION'>CD</scene></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1hb6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1hb6 OCA], [https://pdbe.org/1hb6 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1hb6 RCSB], [https://www.ebi.ac.uk/pdbsum/1hb6 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1hb6 ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
[ | [https://www.uniprot.org/uniprot/ACBP_BOVIN ACBP_BOVIN] Binds medium- and long-chain acyl-CoA esters with very high affinity and may function as an intracellular carrier of acyl-CoA esters. It is also able to displace diazepam from the benzodiazepine (BZD) recognition site located on the GABA type A receptor. It is therefore possible that this protein also acts as a neuropeptide to modulate the action of the GABA receptor.<ref>PMID:11491287</ref> | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: | [[Category: Bos taurus]] | ||
[[Category: | [[Category: Large Structures]] | ||
[[Category: | [[Category: Bergfors T]] | ||
[[Category: | [[Category: Jones TA]] | ||
[[Category: | [[Category: Kleywegt GJ]] | ||
[[Category: | [[Category: Knudsen J]] | ||
[[Category: | [[Category: Zou JY]] | ||