1gwn: Difference between revisions
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==The crystal structure of the core domain of RhoE/Rnd3 - a constitutively activated small G protein== | ==The crystal structure of the core domain of RhoE/Rnd3 - a constitutively activated small G protein== | ||
<StructureSection load='1gwn' size='340' side='right' caption='[[1gwn]], [[Resolution|resolution]] 2.10Å' scene=''> | <StructureSection load='1gwn' size='340' side='right'caption='[[1gwn]], [[Resolution|resolution]] 2.10Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[1gwn]] is a 2 chain structure with sequence from [ | <table><tr><td colspan='2'>[[1gwn]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1GWN OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1GWN FirstGlance]. <br> | ||
</td></tr><tr id=' | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.1Å</td></tr> | ||
<tr id=' | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GTP:GUANOSINE-5-TRIPHOSPHATE'>GTP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1gwn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1gwn OCA], [https://pdbe.org/1gwn PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1gwn RCSB], [https://www.ebi.ac.uk/pdbsum/1gwn PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1gwn ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
[ | [https://www.uniprot.org/uniprot/RND3_MOUSE RND3_MOUSE] Binds GTP but lacks intrinsic GTPase activity and is resistant to Rho-specific GTPase-activating proteins. | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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==See Also== | ==See Also== | ||
*[[GTP-binding protein|GTP-binding protein]] | *[[GTP-binding protein 3D structures|GTP-binding protein 3D structures]] | ||
*[[Rho GTPase|Rho GTPase]] | *[[Rho GTPase 3D structures|Rho GTPase 3D structures]] | ||
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: | [[Category: Large Structures]] | ||
[[Category: Garavini | [[Category: Mus musculus]] | ||
[[Category: Keep | [[Category: Garavini H]] | ||
[[Category: McAlister | [[Category: Keep NH]] | ||
[[Category: Phelan | [[Category: McAlister MSB]] | ||
[[Category: Ridley | [[Category: Phelan JP]] | ||
[[Category: Riento | [[Category: Ridley AJ]] | ||
[[Category: Riento K]] | |||