3fb2: Difference between revisions
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==Crystal structure of the human brain alpha spectrin repeats 15 and 16. Northeast Structural Genomics Consortium target HR5563a.== | |||
<StructureSection load='3fb2' size='340' side='right'caption='[[3fb2]], [[Resolution|resolution]] 2.30Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[3fb2]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3FB2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3FB2 FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3Å</td></tr> | |||
== | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr> | ||
[[3fb2]] is a 2 chain structure with sequence from [ | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3fb2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3fb2 OCA], [https://pdbe.org/3fb2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3fb2 RCSB], [https://www.ebi.ac.uk/pdbsum/3fb2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3fb2 ProSAT], [https://www.topsan.org/Proteins/NESGC/3fb2 TOPSAN]</span></td></tr> | ||
</table> | |||
== Disease == | |||
[https://www.uniprot.org/uniprot/SPTN1_HUMAN SPTN1_HUMAN] West syndrome. The disease is caused by mutations affecting the gene represented in this entry. | |||
== Function == | |||
[https://www.uniprot.org/uniprot/SPTN1_HUMAN SPTN1_HUMAN] Fodrin, which seems to be involved in secretion, interacts with calmodulin in a calcium-dependent manner and is thus candidate for the calcium-dependent movement of the cytoskeleton at the membrane. | |||
==See Also== | ==See Also== | ||
*[[Spectrin|Spectrin]] | *[[Spectrin 3D structures|Spectrin 3D structures]] | ||
__TOC__ | |||
</StructureSection> | |||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Acton | [[Category: Large Structures]] | ||
[[Category: Ciccosanti | [[Category: Acton TB]] | ||
[[Category: Foote | [[Category: Ciccosanti C]] | ||
[[Category: Hunt | [[Category: Foote EL]] | ||
[[Category: Janjua | [[Category: Hunt JF]] | ||
[[Category: Montelione | [[Category: Janjua H]] | ||
[[Category: Montelione GT]] | |||
[[Category: Seetharaman | [[Category: Seetharaman J]] | ||
[[Category: Shastry | [[Category: Shastry R]] | ||
[[Category: Su | [[Category: Su M]] | ||
[[Category: Tong | [[Category: Tong L]] | ||
[[Category: Vorobiev | [[Category: Vorobiev SM]] | ||
[[Category: Xiao | [[Category: Xiao R]] | ||