1xop: Difference between revisions

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 ==NMR structure of G1V mutant of influenza hemagglutinin fusion peptide in DPC micelles at pH 5==
-<StructureSection load='1xop' size='340' side='right' caption='[[1xop]], [[NMR_Ensembles_of_Models | 25 NMR models]]' scene=''>
+<StructureSection load='1xop' size='340' side='right'caption='[[1xop]]' scene=''>
 == Structural highlights ==
-<table><tr><td colspan='2'>[[1xop]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1XOP OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1XOP FirstGlance]. <br>
+<table><tr><td colspan='2'>[[1xop]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Influenza_A_virus_(A/Netherlands/284/03(H7N7)) Influenza A virus (A/Netherlands/284/03(H7N7))]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1XOP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1XOP FirstGlance]. <br>
-</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1xoo|1xoo]]</td></tr>
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
-<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1xop FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1xop OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1xop RCSB], [http://www.ebi.ac.uk/pdbsum/1xop PDBsum]</span></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1xop FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1xop OCA], [https://pdbe.org/1xop PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1xop RCSB], [https://www.ebi.ac.uk/pdbsum/1xop PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1xop ProSAT]</span></td></tr>
 </table>
+== Function ==
+[https://www.uniprot.org/uniprot/Q6VMJ8_9INFA Q6VMJ8_9INFA] Binds to sialic acid-containing receptors on the cell surface, bringing about the attachment of the virus particle to the cell. This attachment induces virion internalization of about two third of the virus particles through clathrin-dependent endocytosis and about one third through a clathrin- and caveolin-independent pathway. Plays a major role in the determination of host range restriction and virulence. Class I viral fusion protein. Responsible for penetration of the virus into the cell cytoplasm by mediating the fusion of the membrane of the endocytosed virus particle with the endosomal membrane. Low pH in endosomes induces an irreversible conformational change in HA2, releasing the fusion hydrophobic peptide. Several trimers are required to form a competent fusion pore.[RuleBase:RU003324]
 <div style="background-color:#fffaf0;">
 == Publication Abstract from PubMed ==
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 From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
 </div>
+<div class="pdbe-citations 1xop" style="background-color:#fffaf0;"></div>
+==See Also==
+*[[Hemagglutinin 3D structures|Hemagglutinin 3D structures]]
 == References ==
 <references/>
 __TOC__
 </StructureSection>
-[[Category: Bushweller, J H.]]
+[[Category: Large Structures]]
-[[Category: Cafiso, D S.]]
+[[Category: Bushweller JH]]
-[[Category: Han, X.]]
+[[Category: Cafiso DS]]
-[[Category: Lai, A L.]]
+[[Category: Han X]]
-[[Category: Li, Y.]]
+[[Category: Lai AL]]
-[[Category: Tamm, L K.]]
+[[Category: Li Y]]
-[[Category: Helix-kink-helix]]
+[[Category: Tamm LK]]
-[[Category: Viral protein]]