7e4y: Difference between revisions

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-'''Unreleased structure'''
-The entry 7e4y is ON HOLD
+==Crystal structure of tubulin in complex with L-DM4-SMe==
+<StructureSection load='7e4y' size='340' side='right'caption='[[7e4y]], [[Resolution|resolution]] 2.71&Aring;' scene=''>
+== Structural highlights ==
+<table><tr><td colspan='2'>[[7e4y]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Bos_taurus Bos taurus], [https://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus] and [https://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7E4Y OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7E4Y FirstGlance]. <br>
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.708&#8491;</td></tr>
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACP:PHOSPHOMETHYLPHOSPHONIC+ACID+ADENYLATE+ESTER'>ACP</scene>, <scene name='pdbligand=BKU:(1S,2S,3S,5R,6S,16E,18E,20S,21R)-11-chloro-21-hydroxy-12,20-dimethoxy-2,5,9,16-tetramethyl-8,23-dioxo-4,24-dioxa-9,22-diazatetracyclo[19.3.1.1~10,14~.0~3,5~]hexacosa-10(26),11,13,16,18-pentaen-6-yl+(2S)-2-{methyl[3-methyl-3-(methyldisulfanyl)butanoyl]amino}propanoate+(non-preferred+name)'>BKU</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=GDP:GUANOSINE-5-DIPHOSPHATE'>GDP</scene>, <scene name='pdbligand=GTP:GUANOSINE-5-TRIPHOSPHATE'>GTP</scene>, <scene name='pdbligand=MES:2-(N-MORPHOLINO)-ETHANESULFONIC+ACID'>MES</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7e4y FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7e4y OCA], [https://pdbe.org/7e4y PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7e4y RCSB], [https://www.ebi.ac.uk/pdbsum/7e4y PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7e4y ProSAT]</span></td></tr>
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/TBA1B_BOVIN TBA1B_BOVIN] Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.
-Authors: Wang, Y., Li, W.
+==See Also==
+*[[Stathmin-4 3D structures|Stathmin-4 3D structures]]
-Description: Crystal structure of tubulin in complex with L-DM4-SMe
+*[[Tubulin 3D Structures|Tubulin 3D Structures]]
-[[Category: Unreleased Structures]]
+*[[Tubulin tyrosine ligase|Tubulin tyrosine ligase]]
-[[Category: Wang, Y]]
+__TOC__
-[[Category: Li, W]]
+</StructureSection>
+[[Category: Bos taurus]]
+[[Category: Gallus gallus]]
+[[Category: Large Structures]]
+[[Category: Rattus norvegicus]]
+[[Category: Li W]]
+[[Category: Wang Y]]