7c5k: Difference between revisions
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<StructureSection load='7c5k' size='340' side='right'caption='[[7c5k]], [[Resolution|resolution]] 2.68Å' scene=''> | <StructureSection load='7c5k' size='340' side='right'caption='[[7c5k]], [[Resolution|resolution]] 2.68Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[7c5k]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/ | <table><tr><td colspan='2'>[[7c5k]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_BL21(DE3) Escherichia coli BL21(DE3)]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7C5K OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7C5K FirstGlance]. <br> | ||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=3PG:3-PHOSPHOGLYCERIC+ACID'>3PG</scene>, <scene name='pdbligand=G3H:GLYCERALDEHYDE-3-PHOSPHATE'>G3H</scene>, <scene name='pdbligand=NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE'>NAD</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene> | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.68Å</td></tr> | ||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=3PG:3-PHOSPHOGLYCERIC+ACID'>3PG</scene>, <scene name='pdbligand=G3H:GLYCERALDEHYDE-3-PHOSPHATE'>G3H</scene>, <scene name='pdbligand=NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE'>NAD</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7c5k FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7c5k OCA], [https://pdbe.org/7c5k PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7c5k RCSB], [https://www.ebi.ac.uk/pdbsum/7c5k PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7c5k ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7c5k FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7c5k OCA], [https://pdbe.org/7c5k PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7c5k RCSB], [https://www.ebi.ac.uk/pdbsum/7c5k PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7c5k ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
[https://www.uniprot.org/uniprot/A0A140NCK4_ECOBD A0A140NCK4_ECOBD] Catalyzes the oxidative phosphorylation of glyceraldehyde 3-phosphate (G3P) to 1,3-bisphosphoglycerate (BPG) using the cofactor NAD. The first reaction step involves the formation of a hemiacetal intermediate between G3P and a cysteine residue, and this hemiacetal intermediate is then oxidized to a thioester, with concomitant reduction of NAD to NADH. The reduced NADH is then exchanged with the second NAD, and the thioester is attacked by a nucleophilic inorganic phosphate to produce BPG.[ARBA:ARBA00003501] | |||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: Bao | [[Category: Bao LY]] | ||
[[Category: Bostrom | [[Category: Bostrom IK]] | ||
[[Category: Chen | [[Category: Chen AQ]] | ||
[[Category: Gu | [[Category: Gu SH]] | ||
[[Category: Ji | [[Category: Ji CN]] | ||
[[Category: Li | [[Category: Li JX]] | ||
[[Category: Liu | [[Category: Liu MR]] | ||
[[Category: Wang | [[Category: Wang YD]] | ||
[[Category: Yao | [[Category: Yao YC]] | ||
[[Category: Zhang | [[Category: Zhang L]] | ||