6lvh: Difference between revisions

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New page: '''Unreleased structure''' The entry 6lvh is ON HOLD Authors: Addlagatta, A., Sandeep, C.B. Description: Crystal structure of methionine aminopeptidase from Pyrococcus furiosus [[Categ...
 
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'''Unreleased structure'''


The entry 6lvh is ON HOLD
==Crystal structure of methionine aminopeptidase from Pyrococcus furiosus==
<StructureSection load='6lvh' size='340' side='right'caption='[[6lvh]], [[Resolution|resolution]] 3.20&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[6lvh]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Pyrococcus_furiosus_DSM_3638 Pyrococcus furiosus DSM 3638]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6LVH OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6LVH FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.2&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6lvh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6lvh OCA], [https://pdbe.org/6lvh PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6lvh RCSB], [https://www.ebi.ac.uk/pdbsum/6lvh PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6lvh ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/MAP2_PYRFU MAP2_PYRFU] Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val).[HAMAP-Rule:MF_01975]<ref>PMID:9399590</ref>


Authors: Addlagatta, A., Sandeep, C.B.
==See Also==
 
*[[Aminopeptidase 3D structures|Aminopeptidase 3D structures]]
Description: Crystal structure of methionine aminopeptidase from Pyrococcus furiosus
== References ==
[[Category: Unreleased Structures]]
<references/>
[[Category: Addlagatta, A]]
__TOC__
[[Category: Sandeep, C.B]]
</StructureSection>
[[Category: Large Structures]]
[[Category: Pyrococcus furiosus DSM 3638]]
[[Category: Addlagatta A]]
[[Category: Sandeep CB]]

Latest revision as of 17:56, 29 November 2023

Crystal structure of methionine aminopeptidase from Pyrococcus furiosusCrystal structure of methionine aminopeptidase from Pyrococcus furiosus

Structural highlights

6lvh is a 1 chain structure with sequence from Pyrococcus furiosus DSM 3638. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 3.2Å
Ligands:
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

MAP2_PYRFU Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val).[HAMAP-Rule:MF_01975][1]

See Also

References

  1. Tsunasawa S, Izu Y, Miyagi M, Kato I. Methionine aminopeptidase from the hyperthermophilic Archaeon Pyrococcus furiosus: molecular cloning and overexpression in Escherichia coli of the gene, and characteristics of the enzyme. J Biochem. 1997 Oct;122(4):843-50. PMID:9399590 doi:10.1093/oxfordjournals.jbchem.a021831

6lvh, resolution 3.20Å

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OCA