1ess: Difference between revisions

← Older edit

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

OCA

@@ Line 1: / Line 1: @@
-{{Seed}}
-[[Image:1ess.png|left|200px]]
-<!--
+==STEROID TETHERED DNA, NMR, MINIMIZED AVERAGE STRUCTURE==
-The line below this paragraph, containing "STRUCTURE_1ess", creates the "Structure Box" on the page.
+<StructureSection load='1ess' size='340' side='right'caption='[[1ess]]' scene=''>
-You may change the PDB parameter (which sets the PDB file loaded into the applet)
+== Structural highlights ==
-or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+<table><tr><td colspan='2'>[[1ess]] is a 3 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ESS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1ESS FirstGlance]. <br>
-or leave the SCENE parameter empty for the default display.
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
--->
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ESO:O3-PHOSPHONOESTRONE'>ESO</scene></td></tr>
-{{STRUCTURE_1ess|  PDB=1ess  |  SCENE=  }}
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1ess FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ess OCA], [https://pdbe.org/1ess PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1ess RCSB], [https://www.ebi.ac.uk/pdbsum/1ess PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1ess ProSAT]</span></td></tr>
+</table>
+<div style="background-color:#fffaf0;">
+== Publication Abstract from PubMed ==
+The solution structure of an estrone (Es)-tethered tandem DNA duplex consisting of two Es-tethered tetranucleotides and a target octameric DNA sequence is reported. The structure of this Es-tethered tandem duplex has been compared with a corresponding natural tandem duplex without estrones. The Tm of the 3'-Es-tethered tetranucleotide part of the tandem duplex increases by 5 degrees C, whereas the Tm of the 5'-Es-tethered tetranucleotide part increases by 7 degrees C, compared with the corresponding natural counterpart. The NMR structures of both the Es-tethered tandem duplex and the natural counterpart have been based on 24 experimental NMR constraints per residue. Despite the fact that there is considerable distortion at the junction of two Es-tethered tetranucleotides in the major groove of the Es-tethered DNA duplex compared to the natural counterpart, both duplexes do take up B-type DNA structures. It is likely that the spatial proximity of two Es residues, and the resulting hydrophobic interaction between them might be responsible for the increase of the thermal stability of the Es-tethered tandem duplex in comparison with the natural counterpart.
-===STEROID TETHERED DNA, NMR, MINIMIZED AVERAGE STRUCTURE===
+The NMR structure of estrone (Es)-tethered tandem DNA duplex: [d(5'pCAGCp3')-Es] + [Es-d(5'pTCCA3')]: d(5'pTGGAGCTG3').,Denisov AY, Sandstrom A, Maltseva TV, Pyshnyi DV, Ivanova EM, Zarytova VF, Chattopadhyaya J J Biomol Struct Dyn. 1997 Dec;15(3):499-516. PMID:9439997<ref>PMID:9439997</ref>
+From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
-<!--
+</div>
-The line below this paragraph, {{ABSTRACT_PUBMED_9439997}}, adds the Publication Abstract to the page
+<div class="pdbe-citations 1ess" style="background-color:#fffaf0;"></div>
-(as it appears on PubMed at http://www.pubmed.gov), where 9439997 is the PubMed ID number.
+== References ==
--->
+<references/>
-{{ABSTRACT_PUBMED_9439997}}
+__TOC__
+</StructureSection>
-==About this Structure==
+[[Category: Large Structures]]
-Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ESS OCA].
+[[Category: Chattopadhyaya J]]
+[[Category: Denisov A]]
-==Reference==
+[[Category: Ivanova E]]
-The NMR structure of estrone (Es)-tethered tandem DNA duplex: [d(5'pCAGCp3')-Es] + [Es-d(5'pTCCA3')]: d(5'pTGGAGCTG3')., Denisov AY, Sandstrom A, Maltseva TV, Pyshnyi DV, Ivanova EM, Zarytova VF, Chattopadhyaya J, J Biomol Struct Dyn. 1997 Dec;15(3):499-516. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/9439997 9439997]
+[[Category: Maltseva T]]
-[[Category: Chattopadhyaya, J.]]
+[[Category: Pyshnyi D]]
-[[Category: Denisov, A.]]
+[[Category: Sandstrom A]]
-[[Category: Ivanova, E.]]
+[[Category: Zarytova V]]
-[[Category: Maltseva, T.]]
-[[Category: Pyshnyi, D.]]
-[[Category: Sandstrom, A.]]
-[[Category: Zarytova, V.]]
-[[Category: Deoxyribonucleic acid]]
-[[Category: Dna]]
-[[Category: Estrone]]
-[[Category: Nmr]]
-[[Category: Steroid tethered]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul  1 01:52:28 2008''