1d8b: Difference between revisions

<StructureSection load='1d8b' size='340' side='right'caption='[[1d8b]]' scene=''>

<table><tr><td colspan='2'>[[1d8b]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1D8B OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1D8B FirstGlance]. <br>

</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>

<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1d8b FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1d8b OCA], [https://pdbe.org/1d8b PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1d8b RCSB], [https://www.ebi.ac.uk/pdbsum/1d8b PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1d8b ProSAT]</span></td></tr>

[https://www.uniprot.org/uniprot/SGS1_YEAST SGS1_YEAST] Interacts with topoisomerases II and TOP3. Could create a deleterious topological substrate that TOP3 preferentially resolves. The TOP3-SGS1 protein complex may function as a eukaryotic reverse gyrase introducing positive supercoils into extrachromosomal ribosomal DNA rings. Together with topoisomerase II has a role in chromosomal segregation. Maintains rDNA structure where it has a role in re-starting stalled replication forks.<ref>PMID:7969174</ref> <ref>PMID:7736577</ref> <ref>PMID:12228808</ref>  

[[Category: Bork P]]

[[Category: Bottomley MJ]]

[[Category: Linge JP]]

[[Category: Liu Z]]

[[Category: Macias MJ]]

[[Category: Nilges M]]

[[Category: Sattler M]]

[[Category: Stier G]]