5ykn: Difference between revisions

<StructureSection load='5ykn' size='340' side='right'caption='[[5ykn]], [[Resolution|resolution]] 2.30&Aring;' scene=''>

<table><tr><td colspan='2'>[[5ykn]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Arabidopsis_thaliana Arabidopsis thaliana]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5YKN OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5YKN FirstGlance]. <br>

</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3&#8491;</td></tr>

<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NI:NICKEL+(II)+ION'>NI</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>

<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5ykn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5ykn OCA], [https://pdbe.org/5ykn PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5ykn RCSB], [https://www.ebi.ac.uk/pdbsum/5ykn PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5ykn ProSAT]</span></td></tr>

[https://www.uniprot.org/uniprot/JMJ14_ARATH JMJ14_ARATH] Transcriptional repressor (PubMed:25578968). Histone demethylase that demethylates 'Lys-4' (H3K4me) of histone H3 with a higher activity for H3K4me3 and H3K4me2 than H3K4me1. No activity on H3K9me3/2, H3K36me3/2 and H3K27me3/2. Represses FT and TSF expression to inhibit the floral transition. Binds around the transcription start site of the FT locus. Involved in the DRM2-mediated maintenance of DNA methylation, but not required for the de novo DNA methylation. Required for demethylating histone H3K4me3 at the target of RNA silencing. Together with NAC051/NAC052 and NAC050, regulates gene expression and flowering time, probably by the promotion of RNA-mediated gene silencing (PubMed:25578968).<ref>PMID:19946624</ref> <ref>PMID:20177424</ref> <ref>PMID:20202164</ref> <ref>PMID:20478993</ref> <ref>PMID:21052090</ref> <ref>PMID:25578968</ref> <ref>PMID:26617990</ref>  

[[Category: Arabidopsis thaliana]]

[[Category: Large Structures]]

[[Category: Du J]]

[[Category: Yang Z]]