Severin: Difference between revisions

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[[Severin]] is a calcium-activated protein which binds actin. It nucleates actin assembly, severes F-actin  and caps actin filaments. Severin is a member of the calcium-regulated gelsolin superfamily of actin severing and capping proteins<ref>PMID:15060630</ref>. It is named Adseverin and Scinderin as well.  
[[Severin]] is a calcium-activated protein which binds actin. It nucleates actin assembly, severes F-actin  and caps actin filaments. Severin is a member of the calcium-regulated gelsolin superfamily of actin severing and capping proteins<ref>PMID:15060630</ref>. It is named Adseverin and Scinderin as well.  


*<scene name='41/410299/Cv/7'>Ca coordination site</scene>. Water molecules shown as red spheres.
*<scene name='41/410299/Cv/9'>Ca coordination site</scene>. Water molecules are shown as red spheres.
*<scene name='41/410299/Cv/8'>Na coordination site</scene>.  
*<scene name='41/410299/Cv/10'>Na coordination site</scene>.  


</StructureSection>
</StructureSection>


== 3D Structures of Severin ==
== 3D Structures of Severin ==
Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}}
[[3fg6]] – Adseverin C-terminal – human<br />
[[3fg6]] – Adseverin C-terminal – human<br />
[[1svy]] – DdSeverin domain 2 – ''Dictyostelium discoideum'' <br />
[[1svy]] – DdSeverin domain 2 – ''Dictyostelium discoideum'' <br />

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Alexander Berchansky, Michal Harel, Jaime Prilusky