Severin: Difference between revisions

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Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

Alexander Berchansky, Michal Harel, Jaime Prilusky

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-[[Image:Severin.png|left|300px]]
+<StructureSection load='1svy' size='350' side='right' scene='41/410299/Cv/6' caption='Severin domain 2 complex with Ca+2 (green) and Na+ (purple) ions [[1svy]]' pspeed='8'>
-{{STRUCTURE_3fg6|  PDB=3fg6  |  SCENE=Severin/Cv/4 |CAPTION=Severin, [[3fg6]] }}
-[[Severin]] is a calcium-activated protein which binds actin. The images at the top and at the right correspond to one representative Severin structure, ''i.e.'' human Severin ([[3fg6]]). It nucleates actin assembly, severes F-actin  and caps actin filaments. Severin is a member of the calcium-regulated gelsolin superfamily of actin severing and capping proteins. It is named Adseverin and Scinderin as well. The image at the right is the Severin with <scene name='Severin/Cv/5'>calcium ions</scene> (<font color='lime'><b>colored lime</b></font>).
+[[Severin]] is a calcium-activated protein which binds actin. It nucleates actin assembly, severes F-actin  and caps actin filaments. Severin is a member of the calcium-regulated gelsolin superfamily of actin severing and capping proteins<ref>PMID:15060630</ref>. It is named Adseverin and Scinderin as well.
+*<scene name='41/410299/Cv/9'>Ca coordination site</scene>. Water molecules are shown as red spheres.
+*<scene name='41/410299/Cv/10'>Na coordination site</scene>.
+</StructureSection>
 == 3D Structures of Severin ==
+Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}}
 [[3fg6]] – Adseverin C-terminal – human<br />
-[[1svy]] – Severin domain 2 – ''Dictyostelium discoideum'' <br />
+[[1svy]] – DdSeverin domain 2 – ''Dictyostelium discoideum'' <br />
-[[1svq]] - Severin domain 2 - ''Dictyostelium discoideum'', NMR<br />
+[[1svq]], [[1svr]] - DdSeverin domain 2 - NMR<br />
+== References ==
+<references/>
+[[Category:Topic Page]]