5nfa: Difference between revisions
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<StructureSection load='5nfa' size='340' side='right'caption='[[5nfa]], [[Resolution|resolution]] 1.59Å' scene=''> | <StructureSection load='5nfa' size='340' side='right'caption='[[5nfa]], [[Resolution|resolution]] 1.59Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[5nfa]] is a 1 chain structure with sequence from [ | <table><tr><td colspan='2'>[[5nfa]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5NFA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5NFA FirstGlance]. <br> | ||
</td></tr><tr id=' | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.59Å</td></tr> | ||
<tr id=' | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=TVD:N-acetyl-2-(acetylamino)-2-deoxy-beta-D-glucopyranosylamine'>TVD</scene>, <scene name='pdbligand=TVM:3-O-[(3-methoxyphenyl)methyl]-beta-D-galactopyranose'>TVM</scene></td></tr> | ||
< | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5nfa FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5nfa OCA], [https://pdbe.org/5nfa PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5nfa RCSB], [https://www.ebi.ac.uk/pdbsum/5nfa PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5nfa ProSAT]</span></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | |||
</table> | </table> | ||
== Function == | == Function == | ||
[ | [https://www.uniprot.org/uniprot/LEG3_HUMAN LEG3_HUMAN] Galactose-specific lectin which binds IgE. May mediate with the alpha-3, beta-1 integrin the stimulation by CSPG4 of endothelial cells migration. Together with DMBT1, required for terminal differentiation of columnar epithelial cells during early embryogenesis (By similarity). In the nucleus: acts as a pre-mRNA splicing factor. Involved in acute inflammatory responses including neutrophil activation and adhesion, chemoattraction of monocytes macrophages, opsonization of apoptotic neutrophils, and activation of mast cells.<ref>PMID:15181153</ref> <ref>PMID:19594635</ref> <ref>PMID:19616076</ref> | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: | [[Category: Homo sapiens]] | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: Atmanene | [[Category: Atmanene C]] | ||
[[Category: Ciesielski | [[Category: Ciesielski F]] | ||
[[Category: | [[Category: Djedaini Pilard F]] | ||
[[Category: | [[Category: Gautier FM]] | ||
[[Category: | [[Category: Grandjean C]] | ||
[[Category: Ronin C]] | |||
[[Category: Ronin | [[Category: Teletchea S]] | ||
[[Category: Teletchea | [[Category: Vivat Hannah V]] | ||
[[Category: | |||