6a96: Difference between revisions
Jump to navigation
Jump to search
New page: '''Unreleased structure''' The entry 6a96 is ON HOLD Authors: Liu, S., Xu, L., Guan, F., Liu, Y.T., Cui, Y., Zhang, Q., Bi, G.Q., Zhou, Z.H., Zhang, X., Ye, S. Description: Cryo-EM str... |
No edit summary |
||
| (5 intermediate revisions by the same user not shown) | |||
| Line 1: | Line 1: | ||
==Cryo-EM structure of the human alpha5beta3 GABAA receptor in complex with GABA and Nb25== | |||
<SX load='6a96' size='340' side='right' viewer='molstar' caption='[[6a96]], [[Resolution|resolution]] 3.51Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[6a96]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Lama_glama Lama glama]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6A96 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6A96 FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.51Å</td></tr> | |||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ABU:GAMMA-AMINO-BUTANOIC+ACID'>ABU</scene>, <scene name='pdbligand=BMA:BETA-D-MANNOSE'>BMA</scene>, <scene name='pdbligand=MAN:ALPHA-D-MANNOSE'>MAN</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6a96 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6a96 OCA], [https://pdbe.org/6a96 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6a96 RCSB], [https://www.ebi.ac.uk/pdbsum/6a96 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6a96 ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/GBRA5_HUMAN GBRA5_HUMAN] GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel. | |||
==See Also== | |||
*[[GABA receptor 3D structures|GABA receptor 3D structures]] | |||
__TOC__ | |||
[[Category: | </SX> | ||
[[Category: | [[Category: Homo sapiens]] | ||
[[Category: | [[Category: Lama glama]] | ||
[[Category: | [[Category: Large Structures]] | ||
[[Category: Cui | [[Category: Bi GQ]] | ||
[[Category: Guan | [[Category: Cui Y]] | ||
[[Category: Liu | [[Category: Guan F]] | ||
[[Category: Xu | [[Category: Liu S]] | ||
[[Category: | [[Category: Liu YT]] | ||
[[Category: Zhang | [[Category: Xu L]] | ||
[[Category: | [[Category: Ye S]] | ||
[[Category: Zhang Q]] | |||
[[Category: Zhang X]] | |||
[[Category: Zhou ZH]] | |||
Latest revision as of 13:09, 15 November 2023
Cryo-EM structure of the human alpha5beta3 GABAA receptor in complex with GABA and Nb25Cryo-EM structure of the human alpha5beta3 GABAA receptor in complex with GABA and Nb25
| |||||||||