5qhg: Difference between revisions

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-'''Unreleased structure'''
-The entry 5qhg is ON HOLD
+==PanDDA analysis group deposition of models with modelled events (e.g. bound ligands) -- Crystal Structure of NUDT7 in complex with NU000442a==
+<StructureSection load='5qhg' size='340' side='right'caption='[[5qhg]], [[Resolution|resolution]] 1.92&Aring;' scene=''>
-Authors: Krojer, T., Talon, R., Fairhead, M., Diaz Saez, L., Bradley, A.R., Aimon, A., Collins, P., Brandao-Neto, J., Douangamath, A., Spencer, J., London, N., Nelson, A., Brennan, P.E., Huber, K., Bountra, C., Arrowsmith, C.H., Edwards, A., von Delft, F.
+== Structural highlights ==
+<table><tr><td colspan='2'>[[5qhg]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5QHG OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5QHG FirstGlance]. <br>
-Description: PanDDA analysis group deposition of models with modelled events (e.g. bound ligands) --Crystal Structure of NUDT7 in complex with NU000442a
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.92&#8491;</td></tr>
-[[Category: Unreleased Structures]]
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=CSO:S-HYDROXYCYSTEINE'>CSO</scene>, <scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene>, <scene name='pdbligand=H17:2-{3-[(2R)-1-acryloylpyrrolidin-2-yl]phenyl}-N-(3-chlorophenyl)acetamide'>H17</scene>, <scene name='pdbligand=HYP:4-HYDROXYPROLINE'>HYP</scene></td></tr>
-[[Category: Spencer, J]]
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5qhg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5qhg OCA], [https://pdbe.org/5qhg PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5qhg RCSB], [https://www.ebi.ac.uk/pdbsum/5qhg PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5qhg ProSAT]</span></td></tr>
-[[Category: Aimon, A]]
+</table>
-[[Category: Collins, P]]
+== Function ==
-[[Category: Huber, K]]
+[https://www.uniprot.org/uniprot/NUDT7_HUMAN NUDT7_HUMAN] Coenzyme A diphosphatase which mediates the cleavage of CoA, CoA esters and oxidized CoA with similar efficiencies, yielding 3',5'-ADP and the corresponding 4'-phosphopantetheine derivative as products. CoA into 3',5'-ADP and 4'-phosphopantetheine. Has no activity toward NDP-sugars, CDP-alcohols, (deoxy)nucleoside 5'-triphosphates, nucleoside 5'-di or monophosphates, diadenosine polyphosphates, NAD, NADH, NADP, NADPH or thymidine-5'-monophospho-p-nitrophenyl ester. May be required to eliminate oxidized CoA from peroxisomes, or regulate CoA and acyl-CoA levels in this organelle in response to metabolic demand. Does not play a role in U8 snoRNA decapping activity. Binds U8 snoRNA (By similarity).
-[[Category: Arrowsmith, C.H]]
+__TOC__
-[[Category: Brandao-Neto, J]]
+</StructureSection>
-[[Category: Diaz Saez, L]]
+[[Category: Homo sapiens]]
-[[Category: Fairhead, M]]
+[[Category: Large Structures]]
-[[Category: Von Delft, F]]
+[[Category: Aimon A]]
-[[Category: Bradley, A.R]]
+[[Category: Arrowsmith CH]]
-[[Category: Talon, R]]
+[[Category: Bountra C]]
-[[Category: Brennan, P.E]]
+[[Category: Bradley AR]]
-[[Category: Edwards, A]]
+[[Category: Brandao-Neto J]]
-[[Category: Douangamath, A]]
+[[Category: Brennan PE]]
-[[Category: Krojer, T]]
+[[Category: Collins P]]
-[[Category: Bountra, C]]
+[[Category: Diaz Saez L]]
-[[Category: Nelson, A]]
+[[Category: Douangamath A]]
-[[Category: London, N]]
+[[Category: Edwards A]]
+[[Category: Elkins J]]
+[[Category: Fairhead M]]
+[[Category: Huber K]]
+[[Category: Krojer T]]
+[[Category: London N]]
+[[Category: Nelson A]]
+[[Category: Ruda GF]]
+[[Category: Spencer J]]
+[[Category: Srikannathasan V]]
+[[Category: Szommer T]]
+[[Category: Talon R]]
+[[Category: Von Delft F]]