1f3x: Difference between revisions

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==S402P MUTANT OF RABBIT MUSCLE PYRUVATE KINASE==
==S402P MUTANT OF RABBIT MUSCLE PYRUVATE KINASE==
<StructureSection load='1f3x' size='340' side='right' caption='[[1f3x]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
<StructureSection load='1f3x' size='340' side='right'caption='[[1f3x]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[1f3x]] is a 8 chain structure with sequence from [http://en.wikipedia.org/wiki/European_rabbit European rabbit]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1F3X OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1F3X FirstGlance]. <br>
<table><tr><td colspan='2'>[[1f3x]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Oryctolagus_cuniculus Oryctolagus cuniculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1F3X OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1F3X FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=K:POTASSIUM+ION'>K</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene>, <scene name='pdbligand=PYR:PYRUVIC+ACID'>PYR</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.8&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1f3w|1f3w]], [[1pkn|1pkn]]</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=K:POTASSIUM+ION'>K</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene>, <scene name='pdbligand=PYR:PYRUVIC+ACID'>PYR</scene></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Pyruvate_kinase Pyruvate kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.40 2.7.1.40] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1f3x FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1f3x OCA], [https://pdbe.org/1f3x PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1f3x RCSB], [https://www.ebi.ac.uk/pdbsum/1f3x PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1f3x ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1f3x FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1f3x OCA], [http://pdbe.org/1f3x PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1f3x RCSB], [http://www.ebi.ac.uk/pdbsum/1f3x PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1f3x ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/KPYM_RABIT KPYM_RABIT]] Glycolytic enzyme that catalyzes the transfer of a phosphoryl group from phosphoenolpyruvate (PEP) to ADP, generating ATP. Stimulates POU5F1-mediated transcriptional activation (By similarity).  
[https://www.uniprot.org/uniprot/KPYM_RABIT KPYM_RABIT] Glycolytic enzyme that catalyzes the transfer of a phosphoryl group from phosphoenolpyruvate (PEP) to ADP, generating ATP. Stimulates POU5F1-mediated transcriptional activation (By similarity).
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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==See Also==
==See Also==
*[[Pyruvate Kinase|Pyruvate Kinase]]
*[[Pyruvate kinase 3D structures|Pyruvate kinase 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: European rabbit]]
[[Category: Large Structures]]
[[Category: Pyruvate kinase]]
[[Category: Oryctolagus cuniculus]]
[[Category: Czerwinski, E W]]
[[Category: Czerwinski EW]]
[[Category: Fox, R O]]
[[Category: Fox RO]]
[[Category: Friesen, R H.E]]
[[Category: Friesen RHE]]
[[Category: Lee, J C]]
[[Category: Lee JC]]
[[Category: Watowich, S J]]
[[Category: Watowich SJ]]
[[Category: White, M A]]
[[Category: White MA]]
[[Category: Wooll, J O]]
[[Category: Wooll JO]]
[[Category: Muscle isozyme]]
[[Category: S402p]]
[[Category: Transferase]]

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