1a7z: Difference between revisions

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-[[Image:1a7z.jpg|left|200px]]
- {{Structure
+==CRYSTAL STRUCTURE OF ACTINOMYCIN Z3==
-|PDB= 1a7z |SIZE=350|CAPTION= <scene name='initialview01'>1a7z</scene>, resolution 0.95&Aring;
+<StructureSection load='1a7z' size='340' side='right'caption='[[1a7z]], [[Resolution|resolution]] 0.95&Aring;' scene=''>
-|SITE=
+== Structural highlights ==
-|LIGAND= <scene name='pdbligand=BNZ:BENZENE'>BNZ</scene>, <scene name='pdbligand=CTH:4-CHLOROTHREONINE'>CTH</scene>, <scene name='pdbligand=DVA:D-VALINE'>DVA</scene>, <scene name='pdbligand=H5M:TRANS-3-HYDROXY-5-METHYLPROLINE'>H5M</scene>, <scene name='pdbligand=MAA:N-METHYLALANINE'>MAA</scene>, <scene name='pdbligand=MVA:N-METHYLVALINE'>MVA</scene>, <scene name='pdbligand=POM:CIS-5-METHYL-4-OXOPROLINE'>POM</scene>, <scene name='pdbligand=PXZ:2-AMINO-1,9-DICARBONYL-4,6-DIMETHYL-10-DEHYDRO-PHENOXAZIN-3-ONE'>PXZ</scene>, <scene name='pdbligand=SAR:SARCOSINE'>SAR</scene>
+<table><tr><td colspan='2'>[[1a7z]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Streptomyces_fradiae Streptomyces fradiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1A7Z OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1A7Z FirstGlance]. <br>
-|ACTIVITY=
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 0.95&#8491;</td></tr>
-|GENE=
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BNZ:BENZENE'>BNZ</scene>, <scene name='pdbligand=CTH:4-CHLOROTHREONINE'>CTH</scene>, <scene name='pdbligand=DVA:D-VALINE'>DVA</scene>, <scene name='pdbligand=H5M:TRANS-3-HYDROXY-5-METHYLPROLINE'>H5M</scene>, <scene name='pdbligand=MAA:N-METHYL-L-ALANINE'>MAA</scene>, <scene name='pdbligand=MVA:N-METHYLVALINE'>MVA</scene>, <scene name='pdbligand=POM:CIS-5-METHYL-4-OXOPROLINE'>POM</scene>, <scene name='pdbligand=PRD_000009:Actinomycin+Z3'>PRD_000009</scene>, <scene name='pdbligand=PXZ:2-AMINO-1,9-DICARBONYL-4,6-DIMETHYL-10-DEHYDRO-PHENOXAZIN-3-ONE'>PXZ</scene>, <scene name='pdbligand=SAR:SARCOSINE'>SAR</scene></td></tr>
-|DOMAIN=
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1a7z FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1a7z OCA], [https://pdbe.org/1a7z PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1a7z RCSB], [https://www.ebi.ac.uk/pdbsum/1a7z PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1a7z ProSAT]</span></td></tr>
-|RELATEDENTRY=
+</table>
-|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1a7z FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1a7z OCA], [http://www.ebi.ac.uk/pdbsum/1a7z PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1a7z RCSB]</span>
+<div style="background-color:#fffaf0;">
-}}
+== Publication Abstract from PubMed ==
+Untwinned single crystals of the actinomycins D and Z3 that diffracted to atomic resolution could be obtained for the first time. Low-temperature data collection and a new ab initio method for solving the structures led to precise crystal structures which showed, for example, that the unit cell of actinomycin D contains three molecules, two of which are present in the form of a hydrogen-bridged dimer related by a pseudo-twofold axis (see picture).
-'''CRYSTAL STRUCTURE OF ACTINOMYCIN Z3'''
+Crystal Structures of Actinomycin D and Actinomycin Z3.,Schafer M, Sheldrick GM, Bahner I, Lackner H Angew Chem Int Ed Engl. 1998 Sep 18;37(17):2381-2384. doi:, 10.1002/(SICI)1521-3773(19980918)37:17&lt;2381::AID-ANIE2381&gt;3.0.CO;2-L. PMID:29710967<ref>PMID:29710967</ref>
+From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
-==About this Structure==
+</div>
-A7Z is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Streptomyces_fradiae Streptomyces fradiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1A7Z OCA].
+<div class="pdbe-citations 1a7z" style="background-color:#fffaf0;"></div>
-[[Category: Protein complex]]
+== References ==
+<references/>
+__TOC__
+</StructureSection>
+[[Category: Large Structures]]
 [[Category: Streptomyces fradiae]]
-[[Category: Schafer, M.]]
+[[Category: Schafer M]]
-[[Category: actinomycin]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Mar 30 18:35:11 2008''