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==Crystal structure of the Pleckstrin homology domain of Interactor protein for cytohesin exchange factors 1 (IPCEF1)== | ==Crystal structure of the Pleckstrin homology domain of Interactor protein for cytohesin exchange factors 1 (IPCEF1)== | ||
<StructureSection load='5mr1' size='340' side='right' caption='[[5mr1]], [[Resolution|resolution]] 1.20Å' scene=''> | <StructureSection load='5mr1' size='340' side='right'caption='[[5mr1]], [[Resolution|resolution]] 1.20Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[5mr1]] is a 1 chain structure with sequence from [ | <table><tr><td colspan='2'>[[5mr1]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5MR1 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5MR1 FirstGlance]. <br> | ||
</td></tr><tr id=' | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.2Å</td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5mr1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5mr1 OCA], [https://pdbe.org/5mr1 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5mr1 RCSB], [https://www.ebi.ac.uk/pdbsum/5mr1 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5mr1 ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
[ | [https://www.uniprot.org/uniprot/ICEF1_HUMAN ICEF1_HUMAN] Enhances the promotion of guanine-nucleotide exchange by PSCD2 on ARF6 in a concentration-dependent manner. | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: | [[Category: Homo sapiens]] | ||
[[Category: Aitkenhead | [[Category: Large Structures]] | ||
[[Category: Arrowsmith | [[Category: Aitkenhead H]] | ||
[[Category: Bountra | [[Category: Arrowsmith CH]] | ||
[[Category: Burgess-Brown | [[Category: Bountra C]] | ||
[[Category: Edwards | [[Category: Burgess-Brown N]] | ||
[[Category: Gileadi | [[Category: Edwards A]] | ||
[[Category: Newman | [[Category: Gileadi O]] | ||
[[Category: Wang | [[Category: Newman JA]] | ||
[[Category: Williams | [[Category: Wang D]] | ||
[[Category: Von | [[Category: Williams E]] | ||
[[Category: Von Delft F]] | |||
Latest revision as of 20:46, 8 November 2023
Crystal structure of the Pleckstrin homology domain of Interactor protein for cytohesin exchange factors 1 (IPCEF1)Crystal structure of the Pleckstrin homology domain of Interactor protein for cytohesin exchange factors 1 (IPCEF1)
Structural highlights
FunctionICEF1_HUMAN Enhances the promotion of guanine-nucleotide exchange by PSCD2 on ARF6 in a concentration-dependent manner. |
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