5wt9: Difference between revisions

<StructureSection load='5wt9' size='340' side='right'caption='[[5wt9]], [[Resolution|resolution]] 2.40&Aring;' scene=''>

<table><tr><td colspan='2'>[[5wt9]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5WT9 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5WT9 FirstGlance]. <br>

</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.401&#8491;</td></tr>

<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FUC:ALPHA-L-FUCOSE'>FUC</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>

<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5wt9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5wt9 OCA], [https://pdbe.org/5wt9 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5wt9 RCSB], [https://www.ebi.ac.uk/pdbsum/5wt9 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5wt9 ProSAT]</span></td></tr>

[https://www.uniprot.org/uniprot/PDCD1_HUMAN PDCD1_HUMAN] Systemic lupus erythematosus;Multiple sclerosis. Systemic lupus erythematosus 2 (SLEB2) [MIM:[https://omim.org/entry/605218 605218]: A chronic, relapsing, inflammatory, and often febrile multisystemic disorder of connective tissue, characterized principally by involvement of the skin, joints, kidneys and serosal membranes. It is of unknown etiology, but is thought to represent a failure of the regulatory mechanisms of the autoimmune system. The disease is marked by a wide range of system dysfunctions, an elevated erythrocyte sedimentation rate, and the formation of LE cells in the blood or bone marrow. Note=Disease susceptibility is associated with variations affecting the gene represented in this entry.<ref>PMID:12402038</ref>  

[https://www.uniprot.org/uniprot/PDCD1_HUMAN PDCD1_HUMAN] Inhibitory cell surface receptor involved in the regulation of T-cell function during immunity and tolerance. Upon ligand binding, inhibits T-cell effector functions in an antigen-specific manner. Possible cell death inducer, in association with other factors.<ref>PMID:21276005</ref>  

[[Category: Homo sapiens]]

[[Category: Large Structures]]

[[Category: Chai Y]]

[[Category: Gao GF]]

[[Category: Gao S]]

[[Category: Liu WJ]]

[[Category: Qi J]]

[[Category: Shi Y]]

[[Category: Song H]]

[[Category: Tan S]]

[[Category: Tong Z]]

[[Category: Wang Q]]

[[Category: Wang Z]]

[[Category: Wong G]]

[[Category: Yan J]]

[[Category: Yang F]]

[[Category: Zhang H]]

[[Category: Zhu X]]