5avr: Difference between revisions

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==Kinetics by X-ray crystallography: Tl+-substitution of bound K+ in the E2.MgF42-.2K+ crystal after 1.5 min==
==Kinetics by X-ray crystallography: Tl+-substitution of bound K+ in the E2.MgF42-.2K+ crystal after 1.5 min==
<StructureSection load='5avr' size='340' side='right' caption='[[5avr]], [[Resolution|resolution]] 2.70&Aring;' scene=''>
<StructureSection load='5avr' size='340' side='right'caption='[[5avr]], [[Resolution|resolution]] 2.70&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[5avr]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Squalus_acanthias Squalus acanthias]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5AVR OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5AVR FirstGlance]. <br>
<table><tr><td colspan='2'>[[5avr]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Squalus_acanthias Squalus acanthias]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5AVR OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5AVR FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CLR:CHOLESTEROL'>CLR</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene>, <scene name='pdbligand=MF4:TETRAFLUOROMAGNESATE(2-)'>MF4</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=TL:THALLIUM+(I)+ION'>TL</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.7&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5avq|5avq]], [[5avs|5avs]], [[5avt|5avt]], [[5avu|5avu]], [[5avv|5avv]], [[5avw|5avw]], [[5avx|5avx]], [[5avy|5avy]], [[5avz|5avz]], [[5aw0|5aw0]], [[5aw1|5aw1]], [[5aw2|5aw2]], [[5aw3|5aw3]], [[5aw4|5aw4]], [[5aw5|5aw5]], [[5aw6|5aw6]], [[5aw7|5aw7]], [[5aw8|5aw8]], [[5aw9|5aw9]]</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CLR:CHOLESTEROL'>CLR</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene>, <scene name='pdbligand=MF4:TETRAFLUOROMAGNESATE(2-)'>MF4</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=TL:THALLIUM+(I)+ION'>TL</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5avr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5avr OCA], [http://www.rcsb.org/pdb/explore.do?structureId=5avr RCSB], [http://www.ebi.ac.uk/pdbsum/5avr PDBsum]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5avr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5avr OCA], [https://pdbe.org/5avr PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5avr RCSB], [https://www.ebi.ac.uk/pdbsum/5avr PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5avr ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/C4IX13_SQUAC C4IX13_SQUAC]] This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane.[RuleBase:RU004369]  
[https://www.uniprot.org/uniprot/Q4H132_SQUAC Q4H132_SQUAC]  
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
<div class="pdbe-citations 5avr" style="background-color:#fffaf0;"></div>
==See Also==
*[[ATPase 3D structures|ATPase 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Squalus acanthias]]
[[Category: Squalus acanthias]]
[[Category: Cornelius, F]]
[[Category: Cornelius F]]
[[Category: Hirata, A]]
[[Category: Hirata A]]
[[Category: Ogawa, H]]
[[Category: Ogawa H]]
[[Category: Toyoshima, C]]
[[Category: Toyoshima C]]
[[Category: Atp-binding]]
[[Category: Atpase]]
[[Category: Haloacid dehydrogenease superfamily]]
[[Category: Hydrolase]]
[[Category: Hydrolase-transport protein complex]]
[[Category: Ion pump]]
[[Category: Ion transport]]
[[Category: K+ binding]]
[[Category: Kinetic]]
[[Category: Membrane protein]]
[[Category: Nucleotide-binding]]
[[Category: Phosphate analogue]]
[[Category: Phosphoprotein]]

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