4yyl: Difference between revisions

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==Phenolic acid derivative bound to influenza strain H1N1 polymerase subunit PA endonuclease==
==Phenolic acid derivative bound to influenza strain H1N1 polymerase subunit PA endonuclease==
<StructureSection load='4yyl' size='340' side='right' caption='[[4yyl]], [[Resolution|resolution]] 1.91&Aring;' scene=''>
<StructureSection load='4yyl' size='340' side='right'caption='[[4yyl]], [[Resolution|resolution]] 1.91&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[4yyl]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4YYL OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4YYL FirstGlance]. <br>
<table><tr><td colspan='2'>[[4yyl]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Influenza_A_virus_(A/Puerto_Rico/8/1934(H1N1)) Influenza A virus (A/Puerto Rico/8/1934(H1N1))]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4YYL OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4YYL FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=4KN:2-(4-FLUOROPHENOXY)-1-(2,3,4-TRIHYDROXYPHENYL)ETHANONE'>4KN</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.905&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4yyl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4yyl OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4yyl RCSB], [http://www.ebi.ac.uk/pdbsum/4yyl PDBsum]</span></td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=4KN:2-(4-FLUOROPHENOXY)-1-(2,3,4-TRIHYDROXYPHENYL)ETHANONE'>4KN</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4yyl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4yyl OCA], [https://pdbe.org/4yyl PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4yyl RCSB], [https://www.ebi.ac.uk/pdbsum/4yyl PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4yyl ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/PA_I34A1 PA_I34A1]] Implicated in endonuclease cleavage of capped RNA primers. Displays an elongation factor activity in viral RNA synthesis. Dispensable for viral transcription, but not replication.  
[https://www.uniprot.org/uniprot/PA_I34A1 PA_I34A1] Implicated in endonuclease cleavage of capped RNA primers. Displays an elongation factor activity in viral RNA synthesis. Dispensable for viral transcription, but not replication.
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
<div class="pdbe-citations 4yyl" style="background-color:#fffaf0;"></div>
==See Also==
*[[RNA polymerase 3D structures|RNA polymerase 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Fudo, S]]
[[Category: Large Structures]]
[[Category: Hoshino, T]]
[[Category: Fudo S]]
[[Category: Neya, S]]
[[Category: Hoshino T]]
[[Category: Nukaga, M]]
[[Category: Neya S]]
[[Category: Odagiri, T]]
[[Category: Nukaga M]]
[[Category: Tashiro, M]]
[[Category: Odagiri T]]
[[Category: Yamamoto, N]]
[[Category: Tashiro M]]
[[Category: Hydrolase-hydrolase inhibitor complex]]
[[Category: Yamamoto N]]

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