Proteopedia

4ysx: Difference between revisions

← Older edit
No edit summary
No edit summary
 
(2 intermediate revisions by the same user not shown)
Line 1: Line 1:


==Crystal structure of Mitochondrial rhodoquinol-fumarate reductase from Ascaris suum with the specific inhibitor NN23==
==Crystal structure of Mitochondrial rhodoquinol-fumarate reductase from Ascaris suum with the specific inhibitor NN23==
<StructureSection load='4ysx' size='340' side='right' caption='[[4ysx]], [[Resolution|resolution]] 2.25&Aring;' scene=''>
<StructureSection load='4ysx' size='340' side='right'caption='[[4ysx]], [[Resolution|resolution]] 2.25&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[4ysx]] is a 8 chain structure with sequence from [http://en.wikipedia.org/wiki/Ascaris_suum Ascaris suum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4YSX OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4YSX FirstGlance]. <br>
<table><tr><td colspan='2'>[[4ysx]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Ascaris_suum Ascaris suum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4YSX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4YSX FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=E23:N-(4-TERT-BUTYLBENZYL)-2-(TRIFLUOROMETHYL)BENZAMIDE'>E23</scene>, <scene name='pdbligand=EPH:L-ALPHA-PHOSPHATIDYL-BETA-OLEOYL-GAMMA-PALMITOYL-PHOSPHATIDYLETHANOLAMINE'>EPH</scene>, <scene name='pdbligand=F3S:FE3-S4+CLUSTER'>F3S</scene>, <scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene>, <scene name='pdbligand=FES:FE2/S2+(INORGANIC)+CLUSTER'>FES</scene>, <scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene>, <scene name='pdbligand=MLI:MALONATE+ION'>MLI</scene>, <scene name='pdbligand=SF4:IRON/SULFUR+CLUSTER'>SF4</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.25&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3vr8|3vr8]], [[3vrb|3vrb]], [[3ae8|3ae8]], [[3ae7|3ae7]], [[3ae5|3ae5]], [[3ae9|3ae9]], [[4ysy|4ysy]], [[4ysz|4ysz]], [[4yt0|4yt0]], [[4ytm|4ytm]], [[4ytn|4ytn]], [[4ytp|4ytp]], [[4yxd|4yxd]]</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=E23:N-(4-TERT-BUTYLBENZYL)-2-(TRIFLUOROMETHYL)BENZAMIDE'>E23</scene>, <scene name='pdbligand=EPH:L-ALPHA-PHOSPHATIDYL-BETA-OLEOYL-GAMMA-PALMITOYL-PHOSPHATIDYLETHANOLAMINE'>EPH</scene>, <scene name='pdbligand=F3S:FE3-S4+CLUSTER'>F3S</scene>, <scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene>, <scene name='pdbligand=FES:FE2/S2+(INORGANIC)+CLUSTER'>FES</scene>, <scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene>, <scene name='pdbligand=MLI:MALONATE+ION'>MLI</scene>, <scene name='pdbligand=SF4:IRON/SULFUR+CLUSTER'>SF4</scene></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Succinate_dehydrogenase_(quinone) Succinate dehydrogenase (quinone)], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.3.5.1 1.3.5.1] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4ysx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ysx OCA], [https://pdbe.org/4ysx PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4ysx RCSB], [https://www.ebi.ac.uk/pdbsum/4ysx PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4ysx ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ysx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ysx OCA], [http://pdbe.org/4ysx PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4ysx RCSB], [http://www.ebi.ac.uk/pdbsum/4ysx PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4ysx ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/DHSD_ASCSU DHSD_ASCSU]] Membrane-anchoring subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q) (By similarity). [[http://www.uniprot.org/uniprot/U1LRQ3_ASCSU U1LRQ3_ASCSU]] Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q).[RuleBase:RU362051]  
[https://www.uniprot.org/uniprot/Q33862_ASCSU Q33862_ASCSU]  
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
Line 20: Line 19:
</div>
</div>
<div class="pdbe-citations 4ysx" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 4ysx" style="background-color:#fffaf0;"></div>
==See Also==
*[[Succinate dehydrogenase 3D structures|Succinate dehydrogenase 3D structures]]
== References ==
== References ==
<references/>
<references/>
Line 25: Line 27:
</StructureSection>
</StructureSection>
[[Category: Ascaris suum]]
[[Category: Ascaris suum]]
[[Category: Harada, S]]
[[Category: Large Structures]]
[[Category: Honma, T]]
[[Category: Harada S]]
[[Category: Inaoka, D K]]
[[Category: Honma T]]
[[Category: Inoue, M]]
[[Category: Inaoka DK]]
[[Category: Kita, K]]
[[Category: Inoue M]]
[[Category: Nagahama, M]]
[[Category: Kita K]]
[[Category: Sakamoto, K]]
[[Category: Nagahama M]]
[[Category: Sato, D]]
[[Category: Sakamoto K]]
[[Category: Shiba, T]]
[[Category: Sato D]]
[[Category: Yamamoto, A]]
[[Category: Shiba T]]
[[Category: Yone, A]]
[[Category: Yamamoto A]]
[[Category: Complex ii]]
[[Category: Yone A]]
[[Category: Oxidoreductase-oxidoreductase inhibitor complex]]
[[Category: Rhodoquinol-fumarate reductase]]

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

OCA
Retrieved from "https://proteopedia.openfox.io/w/4ysx"