4o4t: Difference between revisions

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OCA

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 ==MURINE NEUROGLOBIN UNDER XENON PRESSURE 30 bar==
-<StructureSection load='4o4t' size='340' side='right' caption='[[4o4t]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
+<StructureSection load='4o4t' size='340' side='right'caption='[[4o4t]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
 == Structural highlights ==
-<table><tr><td colspan='2'>[[4o4t]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4O4T OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4O4T FirstGlance]. <br>
+<table><tr><td colspan='2'>[[4o4t]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4O4T OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4O4T FirstGlance]. <br>
-</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=XE:XENON'>XE</scene></td></tr>
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9&#8491;</td></tr>
-<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4o4z|4o4z]], [[4nwh|4nwh]], [[4nwe|4nwe]], [[4nxa|4nxa]], [[4nxc|4nxc]]</td></tr>
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=XE:XENON'>XE</scene></td></tr>
-<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4o4t FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4o4t OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4o4t RCSB], [http://www.ebi.ac.uk/pdbsum/4o4t PDBsum]</span></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4o4t FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4o4t OCA], [https://pdbe.org/4o4t PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4o4t RCSB], [https://www.ebi.ac.uk/pdbsum/4o4t PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4o4t ProSAT]</span></td></tr>
 </table>
+== Function ==
+[https://www.uniprot.org/uniprot/NGB_MOUSE NGB_MOUSE] Involved in oxygen transport in the brain. Hexacoordinate globin, displaying competitive binding of oxygen or the distal His residue to the iron atom. Not capable of penetrating cell membranes. The deoxygenated form exhibits nitrite reductase activity inhibiting cellular respiration via NO-binding to cytochrome c oxidase. Involved in neuroprotection during oxidative stress. May exert its anti-apoptotic activity by acting to reset the trigger level of mitochondrial cytochrome c release necessary to commit the cells to apoptosis.<ref>PMID:11473111</ref> <ref>PMID:11473128</ref>
 <div style="background-color:#fffaf0;">
 == Publication Abstract from PubMed ==
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 From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
 </div>
+<div class="pdbe-citations 4o4t" style="background-color:#fffaf0;"></div>
+==See Also==
+*[[Neuroglobin|Neuroglobin]]
 == References ==
 <references/>
 __TOC__
 </StructureSection>
-[[Category: Prange, T]]
+[[Category: Large Structures]]
-[[Category: Vallone, B]]
+[[Category: Mus musculus]]
-[[Category: H, N Colloc]]
+[[Category: Colloc'h N]]
-[[Category: Globin]]
+[[Category: Prange T]]
-[[Category: Oxygen storage-transport protein complex]]
+[[Category: Vallone B]]