4n3x: Difference between revisions
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==Crystal structure of Rabex-5 CC domain== | ==Crystal structure of Rabex-5 CC domain== | ||
<StructureSection load='4n3x' size='340' side='right' caption='[[4n3x]], [[Resolution|resolution]] 2.00Å' scene=''> | <StructureSection load='4n3x' size='340' side='right'caption='[[4n3x]], [[Resolution|resolution]] 2.00Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[4n3x]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4N3X OCA]. For a <b>guided tour on the structure components</b> use [ | <table><tr><td colspan='2'>[[4n3x]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4N3X OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4N3X FirstGlance]. <br> | ||
</td></tr><tr id=' | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2Å</td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4n3x FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4n3x OCA], [https://pdbe.org/4n3x PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4n3x RCSB], [https://www.ebi.ac.uk/pdbsum/4n3x PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4n3x ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
[ | [https://www.uniprot.org/uniprot/RABX5_HUMAN RABX5_HUMAN] Rab effector protein acting as linker between gamma-adaptin, RAB4A or RAB5A. Involved in endocytic membrane fusion and membrane trafficking of recycling endosomes. Stimulates nucleotide exchange on RAB5A. Can act as a ubiquitin ligase (By similarity).<ref>PMID:9323142</ref> <ref>PMID:11452015</ref> <ref>PMID:15339665</ref> | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: | [[Category: Homo sapiens]] | ||
[[Category: | [[Category: Large Structures]] | ||
[[Category: | [[Category: Ding J]] | ||
[[Category: | [[Category: Zhang T]] | ||
[[Category: | [[Category: Zhang Z]] | ||