4mm2: Difference between revisions
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==Crystal structure of yeast primase catalytic subunit== | ==Crystal structure of yeast primase catalytic subunit== | ||
<StructureSection load='4mm2' size='340' side='right' caption='[[4mm2]], [[Resolution|resolution]] 1.60Å' scene=''> | <StructureSection load='4mm2' size='340' side='right'caption='[[4mm2]], [[Resolution|resolution]] 1.60Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[4mm2]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4MM2 OCA]. For a <b>guided tour on the structure components</b> use [ | <table><tr><td colspan='2'>[[4mm2]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae_S288C Saccharomyces cerevisiae S288C]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4MM2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4MM2 FirstGlance]. <br> | ||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CD:CADMIUM+ION'>CD</scene>, <scene name='pdbligand=CIT:CITRIC+ACID'>CIT</scene></td></tr> | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.6Å</td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CD:CADMIUM+ION'>CD</scene>, <scene name='pdbligand=CIT:CITRIC+ACID'>CIT</scene></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4mm2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4mm2 OCA], [https://pdbe.org/4mm2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4mm2 RCSB], [https://www.ebi.ac.uk/pdbsum/4mm2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4mm2 ProSAT]</span></td></tr> | |||
</table> | </table> | ||
== Function == | == Function == | ||
[ | [https://www.uniprot.org/uniprot/PRI1_YEAST PRI1_YEAST] DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments made during discontinuous DNA replication. In a complex with DNA polymerase alpha (DNA polymerase alpha:primase) constitutes a replicative polymerase. Both primase components participate in formation of the active center, but the ATP-binding site is exclusively located on p48. | ||
==See Also== | |||
*[[RNA polymerase 3D structures|RNA polymerase 3D structures]] | |||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: | [[Category: Large Structures]] | ||
[[Category: | [[Category: Saccharomyces cerevisiae S288C]] | ||
[[Category: | [[Category: An JY]] | ||
[[Category: | [[Category: Eom SH]] | ||
[[Category: | [[Category: Kang JY]] | ||
[[Category: | [[Category: Kim TG]] | ||
[[Category: | [[Category: Lee JG]] | ||
[[Category: | [[Category: Lee Y]] | ||
[[Category: | [[Category: Lim JJ]] | ||
[[Category: | [[Category: Park KR]] | ||
[[Category: | [[Category: Wang J]] | ||
[[Category: | [[Category: Youn HS]] | ||
Latest revision as of 17:43, 8 November 2023
Crystal structure of yeast primase catalytic subunitCrystal structure of yeast primase catalytic subunit
Structural highlights
FunctionPRI1_YEAST DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments made during discontinuous DNA replication. In a complex with DNA polymerase alpha (DNA polymerase alpha:primase) constitutes a replicative polymerase. Both primase components participate in formation of the active center, but the ATP-binding site is exclusively located on p48. See Also |
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