4m6x: Difference between revisions

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 ==Mutant structure of methyltransferase from Streptomyces hygroscopicus complexed with S-adenosyl-L-homocysteine and methylphenylpyruvic acid==
-<StructureSection load='4m6x' size='340' side='right' caption='[[4m6x]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
+<StructureSection load='4m6x' size='340' side='right'caption='[[4m6x]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
 == Structural highlights ==
-<table><tr><td colspan='2'>[[4m6x]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4M6X OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4M6X FirstGlance]. <br>
+<table><tr><td colspan='2'>[[4m6x]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Streptomyces_hygroscopicus Streptomyces hygroscopicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4M6X OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4M6X FirstGlance]. <br>
-</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=56D:(3R)-2-OXO-3-PHENYLBUTANOIC+ACID'>56D</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=FE:FE+(III)+ION'>FE</scene>, <scene name='pdbligand=HF2:(2R)-2-HYDROXY-3-PHENYLPROPANOIC+ACID'>HF2</scene>, <scene name='pdbligand=SAH:S-ADENOSYL-L-HOMOCYSTEINE'>SAH</scene><br>
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3&#8491;</td></tr>
-<tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4kib|4kib]], [[4m6y|4m6y]], [[4m71|4m71]], [[4m72|4m72]], [[4m73|4m73]], [[4m74|4m74]]</td></tr>
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=56D:(3R)-2-OXO-3-PHENYLBUTANOIC+ACID'>56D</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=FE:FE+(III)+ION'>FE</scene>, <scene name='pdbligand=HF2:(2R)-2-HYDROXY-3-PHENYLPROPANOIC+ACID'>HF2</scene>, <scene name='pdbligand=SAH:S-ADENOSYL-L-HOMOCYSTEINE'>SAH</scene></td></tr>
-<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4m6x FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4m6x OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4m6x RCSB], [http://www.ebi.ac.uk/pdbsum/4m6x PDBsum]</span></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4m6x FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4m6x OCA], [https://pdbe.org/4m6x PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4m6x RCSB], [https://www.ebi.ac.uk/pdbsum/4m6x PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4m6x ProSAT]</span></td></tr>
-<table>
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/MPPJ_STRHY MPPJ_STRHY] S-adenosyl-L-methionine-dependent methyltransferase involved in synthesis of the nonproteinogenic amino acid (2S,3S)-beta-methyl-phenylalanine, a building block of the antibiotic mannopeptimycin.
 <div style="background-color:#fffaf0;">
 == Publication Abstract from PubMed ==
@@ Line 15: / Line 18: @@
 From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
 </div>
+<div class="pdbe-citations 4m6x" style="background-color:#fffaf0;"></div>
+==See Also==
+*[[SAM-dependent methyltrasferase 3D structures|SAM-dependent methyltrasferase 3D structures]]
 == References ==
 <references/>
 __TOC__
 </StructureSection>
-[[Category: Chan, H C.]]
+[[Category: Large Structures]]
-[[Category: Huang, C J.]]
+[[Category: Streptomyces hygroscopicus]]
-[[Category: Li, T L.]]
+[[Category: Chan HC]]
-[[Category: Liu, Y C.]]
+[[Category: Huang CJ]]
-[[Category: Zou, X W.]]
+[[Category: Li TL]]
-[[Category: Methyltransferase]]
+[[Category: Liu YC]]
-[[Category: Rossmann fold]]
+[[Category: Zou XW]]
-[[Category: Sam/ppy binding]]
-[[Category: Transferase]]