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<StructureSection load='4lmt' size='340' side='right'caption='[[4lmt]], [[Resolution|resolution]] 1.71&Aring;' scene=''>
<StructureSection load='4lmt' size='340' side='right'caption='[[4lmt]], [[Resolution|resolution]] 1.71&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[4lmt]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Cvhoc Cvhoc]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4LMT OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4LMT FirstGlance]. <br>
<table><tr><td colspan='2'>[[4lmt]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Human_coronavirus_OC43 Human coronavirus OC43]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4LMT OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4LMT FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CQD:6-CHLORO-7-{[2-(MORPHOLIN-4-YL)ETHYL]AMINO}QUINOLINE-5,8-DIONE'>CQD</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.71&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4lm7|4lm7]], [[4lm9|4lm9]], [[4lmc|4lmc]]</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CQD:6-CHLORO-7-{[2-(MORPHOLIN-4-YL)ETHYL]AMINO}QUINOLINE-5,8-DIONE'>CQD</scene></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">N ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=31631 CVHOC])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4lmt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4lmt OCA], [https://pdbe.org/4lmt PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4lmt RCSB], [https://www.ebi.ac.uk/pdbsum/4lmt PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4lmt ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4lmt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4lmt OCA], [http://pdbe.org/4lmt PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4lmt RCSB], [http://www.ebi.ac.uk/pdbsum/4lmt PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4lmt ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/Q6SA23_CVHOC Q6SA23_CVHOC]] Major structural component of virions that associates with genomic RNA to form a long, flexible, helical nucleocapsid (By similarity).[PIRNR:PIRNR003888]  
[https://www.uniprot.org/uniprot/NCAP_CVHOC NCAP_CVHOC] Packages the positive strand viral genome RNA into a helical ribonucleocapsid (RNP) and plays a fundamental role during virion assembly through its interactions with the viral genome and membrane protein M. Plays an important role in enhancing the efficiency of subgenomic viral RNA transcription as well as viral replication.[HAMAP-Rule:MF_04096]


==See Also==
==See Also==
*[[Nucleoprotein|Nucleoprotein]]
*[[Nucleoprotein 3D structures|Nucleoprotein 3D structures]]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Cvhoc]]
[[Category: Human coronavirus OC43]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Hou, M H]]
[[Category: Hou MH]]
[[Category: Lin, S Y]]
[[Category: Lin SY]]
[[Category: Liu, C L]]
[[Category: Liu CL]]
[[Category: Hcov-oc43]]
[[Category: N-termainl domain]]
[[Category: Nucleocapsid prtoein]]
[[Category: Rna binding]]
[[Category: Rna binding protein]]

Latest revision as of 17:36, 8 November 2023

Structure of The N-terminal domain of Coronavirus Nucleocapsid Protein complexed with NSC663284Structure of The N-terminal domain of Coronavirus Nucleocapsid Protein complexed with NSC663284

Structural highlights

4lmt is a 1 chain structure with sequence from Human coronavirus OC43. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 1.71Å
Ligands:
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

NCAP_CVHOC Packages the positive strand viral genome RNA into a helical ribonucleocapsid (RNP) and plays a fundamental role during virion assembly through its interactions with the viral genome and membrane protein M. Plays an important role in enhancing the efficiency of subgenomic viral RNA transcription as well as viral replication.[HAMAP-Rule:MF_04096]

See Also

4lmt, resolution 1.71Å

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