4l0o: Difference between revisions
New page: '''Unreleased structure''' The entry 4l0o is ON HOLD Authors: Tarique, K.F., Rehman, S.A.A., Gourinath, S. Description: Structure determination of cystathionine gamma-synthase from Hel... |
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==Structure determination of cystathionine gamma-synthase from Helicobacter pylori== | |||
<StructureSection load='4l0o' size='340' side='right'caption='[[4l0o]], [[Resolution|resolution]] 2.76Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[4l0o]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Helicobacter_pylori_26695 Helicobacter pylori 26695]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4L0O OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4L0O FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.76Å</td></tr> | |||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PLP:PYRIDOXAL-5-PHOSPHATE'>PLP</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4l0o FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4l0o OCA], [https://pdbe.org/4l0o PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4l0o RCSB], [https://www.ebi.ac.uk/pdbsum/4l0o PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4l0o ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/METB_HELPY METB_HELPY] Catalyzes the formation of L-cystathionine from O-succinyl-L-homoserine (OSHS) and L-cysteine, via a gamma-replacement reaction. In the absence of thiol, catalyzes gamma-elimination to form 2-oxobutanoate, succinate and ammonia (By similarity). | |||
==See Also== | |||
*[[Cystathionine gamma synthase|Cystathionine gamma synthase]] | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Helicobacter pylori 26695]] | |||
[[Category: Large Structures]] | |||
[[Category: Gourinath S]] | |||
[[Category: Rehman SAA]] | |||
[[Category: Tarique KF]] | |||