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==Crystal structure of thymidylate synthase from Corynebacterium glutamicum in complex with dUMP== | |||
<StructureSection load='4h0u' size='340' side='right'caption='[[4h0u]], [[Resolution|resolution]] 2.75Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[4h0u]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Corynebacterium_glutamicum_ATCC_13032 Corynebacterium glutamicum ATCC 13032]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4H0U OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4H0U FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.75Å</td></tr> | |||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=UMP:2-DEOXYURIDINE+5-MONOPHOSPHATE'>UMP</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4h0u FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4h0u OCA], [https://pdbe.org/4h0u PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4h0u RCSB], [https://www.ebi.ac.uk/pdbsum/4h0u PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4h0u ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/TYSY_CORGL TYSY_CORGL] Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity). | |||
==See Also== | |||
*[[Thymidylate synthase 3D structures|Thymidylate synthase 3D structures]] | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Corynebacterium glutamicum ATCC 13032]] | |||
[[Category: Large Structures]] | |||
[[Category: Chang CM]] | |||
[[Category: Wang WC]] | |||
Latest revision as of 17:03, 8 November 2023
Crystal structure of thymidylate synthase from Corynebacterium glutamicum in complex with dUMPCrystal structure of thymidylate synthase from Corynebacterium glutamicum in complex with dUMP
Structural highlights
FunctionTYSY_CORGL Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity). See Also |
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