4gh0: Difference between revisions
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==Crystal structure of D48V mutant of human GLTP bound with 12:0 monosulfatide== | ==Crystal structure of D48V mutant of human GLTP bound with 12:0 monosulfatide== | ||
<StructureSection load='4gh0' size='340' side='right' caption='[[4gh0]], [[Resolution|resolution]] 1.35Å' scene=''> | <StructureSection load='4gh0' size='340' side='right'caption='[[4gh0]], [[Resolution|resolution]] 1.35Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[4gh0]] is a 1 chain structure with sequence from [ | <table><tr><td colspan='2'>[[4gh0]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4GH0 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4GH0 FirstGlance]. <br> | ||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EIS:N-{(2S,3R,4E)-3-HYDROXY-1-[(3-O-SULFO-BETA-D-GALACTOPYRANOSYL)OXY]OCTADEC-4-EN-2-YL}DODECANAMIDE'>EIS</scene>, <scene name='pdbligand=MYS:PENTADECANE'>MYS</scene> | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.35Å</td></tr> | ||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EIS:N-{(2S,3R,4E)-3-HYDROXY-1-[(3-O-SULFO-BETA-D-GALACTOPYRANOSYL)OXY]OCTADEC-4-EN-2-YL}DODECANAMIDE'>EIS</scene>, <scene name='pdbligand=MYS:PENTADECANE'>MYS</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4gh0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4gh0 OCA], [https://pdbe.org/4gh0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4gh0 RCSB], [https://www.ebi.ac.uk/pdbsum/4gh0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4gh0 ProSAT]</span></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | |||
</table> | </table> | ||
== Function == | == Function == | ||
[ | [https://www.uniprot.org/uniprot/GLTP_HUMAN GLTP_HUMAN] Accelerates the intermembrane transfer of various glycolipids. Catalyzes the transfer of various glycosphingolipids between membranes but does not catalyze the transfer of phospholipids. May be involved in the intracellular translocation of glucosylceramides.<ref>PMID:18261224</ref> <ref>PMID:15504043</ref> <ref>PMID:17980653</ref> <ref>PMID:15329726</ref> | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | ||
</div> | </div> | ||
<div class="pdbe-citations 4gh0" style="background-color:#fffaf0;"></div> | |||
== References == | == References == | ||
<references/> | <references/> | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Cabo-Bilbao | [[Category: Large Structures]] | ||
[[Category: Malinina | [[Category: Cabo-Bilbao A]] | ||
[[Category: Ochoa-Lizarralde | [[Category: Malinina L]] | ||
[[Category: Popov | [[Category: Ochoa-Lizarralde B]] | ||
[[Category: Samygina | [[Category: Popov AN]] | ||
[[Category: Samygina VR]] | |||