4egx: Difference between revisions
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==Crystal structure of KIF1A CC1-FHA tandem== | ==Crystal structure of KIF1A CC1-FHA tandem== | ||
<StructureSection load='4egx' size='340' side='right' caption='[[4egx]], [[Resolution|resolution]] 2.51Å' scene=''> | <StructureSection load='4egx' size='340' side='right'caption='[[4egx]], [[Resolution|resolution]] 2.51Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[4egx]] is a 4 chain structure with sequence from [ | <table><tr><td colspan='2'>[[4egx]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4EGX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4EGX FirstGlance]. <br> | ||
</td></tr><tr><td class="sblockLbl"><b>[[ | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.51Å</td></tr> | ||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene></td></tr> | |||
<tr><td class="sblockLbl"><b>[[ | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4egx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4egx OCA], [https://pdbe.org/4egx PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4egx RCSB], [https://www.ebi.ac.uk/pdbsum/4egx PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4egx ProSAT]</span></td></tr> | ||
<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | </table> | ||
<table> | == Disease == | ||
[https://www.uniprot.org/uniprot/KIF1A_HUMAN KIF1A_HUMAN] Autosomal dominant nonsyndromic intellectual disability;Hereditary sensory and autonomic neuropathy type 2;Autosomal recessive spastic paraplegia type 30. The disease is caused by mutations affecting the gene represented in this entry.<ref>PMID:21487076</ref> The disease is caused by mutations affecting the gene represented in this entry.<ref>PMID:21820098</ref> The disease is caused by mutations affecting the gene represented in this entry.<ref>PMID:21376300</ref> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/KIF1A_HUMAN KIF1A_HUMAN] Motor for anterograde axonal transport of synaptic vesicle precursors (By similarity). | |||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | ||
</div> | </div> | ||
<div class="pdbe-citations 4egx" style="background-color:#fffaf0;"></div> | |||
==See Also== | |||
*[[Kinesin 3D Structures|Kinesin 3D Structures]] | |||
== References == | == References == | ||
<references/> | <references/> | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Feng | [[Category: Large Structures]] | ||
[[Category: Huo | [[Category: Feng W]] | ||
[[Category: Xu | [[Category: Huo L]] | ||
[[Category: Yu | [[Category: Xu T]] | ||
[[Category: Yue | [[Category: Yu J]] | ||
[[Category: Zhang | [[Category: Yue Y]] | ||
[[Category: Zhang M]] | |||