4egx: Difference between revisions

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==Crystal structure of KIF1A CC1-FHA tandem==
==Crystal structure of KIF1A CC1-FHA tandem==
<StructureSection load='4egx' size='340' side='right' caption='[[4egx]], [[Resolution|resolution]] 2.51&Aring;' scene=''>
<StructureSection load='4egx' size='340' side='right'caption='[[4egx]], [[Resolution|resolution]] 2.51&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[4egx]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4EGX OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4EGX FirstGlance]. <br>
<table><tr><td colspan='2'>[[4egx]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4EGX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4EGX FirstGlance]. <br>
</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene><br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.51&#8491;</td></tr>
<tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4ejq|4ejq]]</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene></td></tr>
<tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">KIF1A, ATSV, C2orf20 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4egx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4egx OCA], [https://pdbe.org/4egx PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4egx RCSB], [https://www.ebi.ac.uk/pdbsum/4egx PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4egx ProSAT]</span></td></tr>
<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4egx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4egx OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4egx RCSB], [http://www.ebi.ac.uk/pdbsum/4egx PDBsum]</span></td></tr>
</table>
<table>
== Disease ==
[https://www.uniprot.org/uniprot/KIF1A_HUMAN KIF1A_HUMAN] Autosomal dominant nonsyndromic intellectual disability;Hereditary sensory and autonomic neuropathy type 2;Autosomal recessive spastic paraplegia type 30. The disease is caused by mutations affecting the gene represented in this entry.<ref>PMID:21487076</ref>  The disease is caused by mutations affecting the gene represented in this entry.<ref>PMID:21820098</ref>  The disease is caused by mutations affecting the gene represented in this entry.<ref>PMID:21376300</ref>
== Function ==
[https://www.uniprot.org/uniprot/KIF1A_HUMAN KIF1A_HUMAN] Motor for anterograde axonal transport of synaptic vesicle precursors (By similarity).
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
<div class="pdbe-citations 4egx" style="background-color:#fffaf0;"></div>
==See Also==
*[[Kinesin 3D Structures|Kinesin 3D Structures]]
== References ==
== References ==
<references/>
<references/>
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</StructureSection>
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Feng, W.]]
[[Category: Large Structures]]
[[Category: Huo, L.]]
[[Category: Feng W]]
[[Category: Xu, T.]]
[[Category: Huo L]]
[[Category: Yu, J.]]
[[Category: Xu T]]
[[Category: Yue, Y.]]
[[Category: Yu J]]
[[Category: Zhang, M.]]
[[Category: Yue Y]]
[[Category: Fha domain]]
[[Category: Zhang M]]
[[Category: Transport protein]]

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