4eax: Difference between revisions

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<StructureSection load='4eax' size='340' side='right'caption='[[4eax]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
<StructureSection load='4eax' size='340' side='right'caption='[[4eax]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[4eax]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4EAX OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4EAX FirstGlance]. <br>
<table><tr><td colspan='2'>[[4eax]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4EAX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4EAX FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=S12:O-[(S)-HYDROXY{[(2S)-2-HYDROXY-3-(OCTADEC-9-ENOYLOXY)PROPYL]OXY}PHOSPHORYL]-L-SERINE'>S12</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4eax FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4eax OCA], [http://pdbe.org/4eax PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4eax RCSB], [http://www.ebi.ac.uk/pdbsum/4eax PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4eax ProSAT]</span></td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=S12:O-[(S)-HYDROXY{[(2S)-2-HYDROXY-3-(OCTADEC-9-ENOYLOXY)PROPYL]OXY}PHOSPHORYL]-L-SERINE'>S12</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4eax FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4eax OCA], [https://pdbe.org/4eax PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4eax RCSB], [https://www.ebi.ac.uk/pdbsum/4eax PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4eax ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/NGF_MOUSE NGF_MOUSE]] Nerve growth factor is important for the development and maintenance of the sympathetic and sensory nervous systems. Extracellular ligand for the NTRK1 and NGFR receptors, activates cellular signaling cascades through those receptor tyrosine kinase to regulate neuronal proliferation, differentiation and survival.  
[https://www.uniprot.org/uniprot/NGF_MOUSE NGF_MOUSE] Nerve growth factor is important for the development and maintenance of the sympathetic and sensory nervous systems. Extracellular ligand for the NTRK1 and NGFR receptors, activates cellular signaling cascades through those receptor tyrosine kinase to regulate neuronal proliferation, differentiation and survival.
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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</div>
</div>
<div class="pdbe-citations 4eax" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 4eax" style="background-color:#fffaf0;"></div>
==See Also==
*[[Nerve growth factor|Nerve growth factor]]
== References ==
== References ==
<references/>
<references/>
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[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Mus musculus]]
[[Category: Mus musculus]]
[[Category: Jiang, T]]
[[Category: Jiang T]]
[[Category: Tong, Q]]
[[Category: Tong Q]]
[[Category: Hormone]]
[[Category: Lyso-p]]
[[Category: Phospholipid]]

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