4e19: Difference between revisions

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-[[Image:4e19.jpg|left|200px]]
-{{STRUCTURE_4e19|  PDB=4e19  |  SCENE=  }}
+==Crystal structure of RNase H1 from halophilic archaeon Halobacterium salinarum NRC-1==
+<StructureSection load='4e19' size='340' side='right'caption='[[4e19]], [[Resolution|resolution]] 1.41&Aring;' scene=''>
+== Structural highlights ==
+<table><tr><td colspan='2'>[[4e19]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Halobacterium_salinarum_NRC-1 Halobacterium salinarum NRC-1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4E19 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4E19 FirstGlance]. <br>
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.41&#8491;</td></tr>
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4e19 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4e19 OCA], [https://pdbe.org/4e19 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4e19 RCSB], [https://www.ebi.ac.uk/pdbsum/4e19 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4e19 ProSAT]</span></td></tr>
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/RNH_HALSA RNH_HALSA] Nuclease that specifically degrades the RNA of RNA-DNA hybrids; seems to act exonucleolytically on RNA/DNA hybrids. Endonucleolytically removes RNA primers from the Okazaki fragments of lagging strand synthesis on its own. Complements the temperature-sensitive phenotype of an E.coli double rnhA/rnhB (RNase H) disruption mutant.<ref>PMID:15115438</ref>
-===Crystal structure of RNase H1 from halophilic archaeon Halobacterium salinarum NRC-1===
+==See Also==
+*[[Ribonuclease 3D structures|Ribonuclease 3D structures]]
+== References ==
-==About this Structure==
+<references/>
-[[4e19]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Halobacterium_sp._nrc-1 Halobacterium sp. nrc-1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4E19 OCA].
+__TOC__
-[[Category: Halobacterium sp. nrc-1]]
+</StructureSection>
-[[Category: Ribonuclease H]]
+[[Category: Halobacterium salinarum NRC-1]]
-[[Category: Angkawidjaja, C.]]
+[[Category: Large Structures]]
-[[Category: Kanaya, S.]]
+[[Category: Angkawidjaja C]]
-[[Category: Koga, Y.]]
+[[Category: Kanaya S]]
-[[Category: You, D J.]]
+[[Category: Koga Y]]
-[[Category: Hydrolase]]
+[[Category: You DJ]]
-[[Category: Rnase h1]]