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==Crystal structure of the core streptavidin mutant V212 (Y22S/N23D/S27D/S45N/Y83S/R84K/E101D/R103K/E116N) complexed with iminobiotin long tail (IMNtail) at 1.7 A resolution==
==Crystal structure of the core streptavidin mutant V212 (Y22S/N23D/S27D/S45N/Y83S/R84K/E101D/R103K/E116N) complexed with iminobiotin long tail (IMNtail) at 1.7 A resolution==
<StructureSection load='3wzq' size='340' side='right' caption='[[3wzq]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
<StructureSection load='3wzq' size='340' side='right'caption='[[3wzq]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[3wzq]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3WZQ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3WZQ FirstGlance]. <br>
<table><tr><td colspan='2'>[[3wzq]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Streptomyces_avidinii Streptomyces avidinii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3WZQ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3WZQ FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=P6G:HEXAETHYLENE+GLYCOL'>P6G</scene>, <scene name='pdbligand=ZOF:6-({5-[(2E,3AS,4S,6AR)-2-IMINOHEXAHYDRO-1H-THIENO[3,4-D]IMIDAZOL-4-YL]PENTANOYL}AMINO)HEXANOIC+ACID'>ZOF</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.7&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3wzn|3wzn]], [[3wzo|3wzo]], [[3wzp|3wzp]]</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=P6G:HEXAETHYLENE+GLYCOL'>P6G</scene>, <scene name='pdbligand=ZOF:6-({5-[(2E,3AS,4S,6AR)-2-IMINOHEXAHYDRO-1H-THIENO[3,4-D]IMIDAZOL-4-YL]PENTANOYL}AMINO)HEXANOIC+ACID'>ZOF</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3wzq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3wzq OCA], [http://pdbe.org/3wzq PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3wzq RCSB], [http://www.ebi.ac.uk/pdbsum/3wzq PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3wzq ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3wzq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3wzq OCA], [https://pdbe.org/3wzq PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3wzq RCSB], [https://www.ebi.ac.uk/pdbsum/3wzq PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3wzq ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/SAV_STRAV SAV_STRAV]] The biological function of streptavidin is not known. Forms a strong non-covalent specific complex with biotin (one molecule of biotin per subunit of streptavidin).  
[https://www.uniprot.org/uniprot/SAV_STRAV SAV_STRAV] The biological function of streptavidin is not known. Forms a strong non-covalent specific complex with biotin (one molecule of biotin per subunit of streptavidin).
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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</div>
</div>
<div class="pdbe-citations 3wzq" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 3wzq" style="background-color:#fffaf0;"></div>
==See Also==
*[[Avidin 3D structures|Avidin 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Doi, H]]
[[Category: Large Structures]]
[[Category: Inoue, T]]
[[Category: Streptomyces avidinii]]
[[Category: Kanai, M]]
[[Category: Doi H]]
[[Category: Kawato, T]]
[[Category: Inoue T]]
[[Category: Kodama, T]]
[[Category: Kanai M]]
[[Category: Matsumura, H]]
[[Category: Kawato T]]
[[Category: Matsuoka, M]]
[[Category: Kodama T]]
[[Category: Meshizuka, T]]
[[Category: Matsumura H]]
[[Category: Mizohata, E]]
[[Category: Matsuoka M]]
[[Category: Shimizu, Y]]
[[Category: Meshizuka T]]
[[Category: Sugiyama, A]]
[[Category: Mizohata E]]
[[Category: Takasu, N]]
[[Category: Shimizu Y]]
[[Category: Tsumoto, K]]
[[Category: Sugiyama A]]
[[Category: Yamamoto, T]]
[[Category: Takasu N]]
[[Category: Beta-barrel]]
[[Category: Tsumoto K]]
[[Category: Biotin binding protein]]
[[Category: Yamamoto T]]

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