3wxq: Difference between revisions

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 ==Serial femtosecond X-ray structure of human fatty acid-binding protein type-3 (FABP3) in complex with stearic acid (C18:0) determined using X-ray free-electron laser at SACLA==
-<StructureSection load='3wxq' size='340' side='right' caption='[[3wxq]], [[Resolution|resolution]] 1.60&Aring;' scene=''>
+<StructureSection load='3wxq' size='340' side='right'caption='[[3wxq]], [[Resolution|resolution]] 1.60&Aring;' scene=''>
 == Structural highlights ==
-<table><tr><td colspan='2'>[[3wxq]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3WXQ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3WXQ FirstGlance]. <br>
+<table><tr><td colspan='2'>[[3wxq]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3WXQ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3WXQ FirstGlance]. <br>
-</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=STE:STEARIC+ACID'>STE</scene></td></tr>
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.6&#8491;</td></tr>
-<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3wvm|3wvm]], [[3wul|3wul]], [[3wum|3wum]], [[3wxs|3wxs]], [[3wxt|3wxt]], [[3wxu|3wxu]], [[4w4q|4w4q]]</td></tr>
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=STE:STEARIC+ACID'>STE</scene></td></tr>
-<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3wxq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3wxq OCA], [http://pdbe.org/3wxq PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3wxq RCSB], [http://www.ebi.ac.uk/pdbsum/3wxq PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3wxq ProSAT]</span></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3wxq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3wxq OCA], [https://pdbe.org/3wxq PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3wxq RCSB], [https://www.ebi.ac.uk/pdbsum/3wxq PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3wxq ProSAT]</span></td></tr>
 </table>
 == Function ==
-[[http://www.uniprot.org/uniprot/FABPH_HUMAN FABPH_HUMAN]] FABP are thought to play a role in the intracellular transport of long-chain fatty acids and their acyl-CoA esters.
+[https://www.uniprot.org/uniprot/FABPH_HUMAN FABPH_HUMAN] FABP are thought to play a role in the intracellular transport of long-chain fatty acids and their acyl-CoA esters.
+<div style="background-color:#fffaf0;">
+== Publication Abstract from PubMed ==
+Serial femtosecond X-ray crystallography (SFX) has revolutionized atomic-resolution structural investigation by expanding applicability to micrometer-sized protein crystals, even at room temperature, and by enabling dynamics studies. However, reliable crystal-carrying media for SFX are lacking. Here we introduce a grease-matrix carrier for protein microcrystals and obtain the structures of lysozyme, glucose isomerase, thaumatin and fatty acid-binding protein type 3 under ambient conditions at a resolution of or finer than 2 A.
+Grease matrix as a versatile carrier of proteins for serial crystallography.,Sugahara M, Mizohata E, Nango E, Suzuki M, Tanaka T, Masuda T, Tanaka R, Shimamura T, Tanaka Y, Suno C, Ihara K, Pan D, Kakinouchi K, Sugiyama S, Murata M, Inoue T, Tono K, Song C, Park J, Kameshima T, Hatsui T, Joti Y, Yabashi M, Iwata S Nat Methods. 2014 Nov 10. doi: 10.1038/nmeth.3172. PMID:25384243<ref>PMID:25384243</ref>
+From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
+</div>
+<div class="pdbe-citations 3wxq" style="background-color:#fffaf0;"></div>
+==See Also==
+*[[Fatty acid-binding protein 3D structures|Fatty acid-binding protein 3D structures]]
+== References ==
+<references/>
 __TOC__
 </StructureSection>
-[[Category: Hatsui, T]]
+[[Category: Homo sapiens]]
-[[Category: Iwata, S]]
+[[Category: Large Structures]]
-[[Category: Joti, Y]]
+[[Category: Hatsui T]]
-[[Category: Kakinouchi, K]]
+[[Category: Iwata S]]
-[[Category: Mizohata, E]]
+[[Category: Joti Y]]
-[[Category: Murata, M]]
+[[Category: Kakinouchi K]]
-[[Category: Nango, E]]
+[[Category: Mizohata E]]
-[[Category: Song, C]]
+[[Category: Murata M]]
-[[Category: Sugahara, M]]
+[[Category: Nango E]]
-[[Category: Sugiyama, S]]
+[[Category: Song C]]
-[[Category: Suzuki, M]]
+[[Category: Sugahara M]]
-[[Category: Tanaka, R]]
+[[Category: Sugiyama S]]
-[[Category: Tanaka, T]]
+[[Category: Suzuki M]]
-[[Category: Tono, K]]
+[[Category: Tanaka R]]
-[[Category: Yabashi, M]]
+[[Category: Tanaka T]]
-[[Category: Antiparallel beta barrel]]
+[[Category: Tono K]]
-[[Category: Heart]]
+[[Category: Yabashi M]]
-[[Category: Intracellular transport]]
-[[Category: Transport protein]]