3wo4: Difference between revisions
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==Crystal structure of the IL-18 signaling ternary complex== | ==Crystal structure of the IL-18 signaling ternary complex== | ||
<StructureSection load='3wo4' size='340' side='right' caption='[[3wo4]], [[Resolution|resolution]] 3.10Å' scene=''> | <StructureSection load='3wo4' size='340' side='right'caption='[[3wo4]], [[Resolution|resolution]] 3.10Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[3wo4]] is a 3 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3WO4 OCA]. For a <b>guided tour on the structure components</b> use [ | <table><tr><td colspan='2'>[[3wo4]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3WO4 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3WO4 FirstGlance]. <br> | ||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BMA:BETA-D-MANNOSE'>BMA</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand= | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.1Å</td></tr> | ||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BMA:BETA-D-MANNOSE'>BMA</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=FUC:ALPHA-L-FUCOSE'>FUC</scene>, <scene name='pdbligand=MAN:ALPHA-D-MANNOSE'>MAN</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3wo4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3wo4 OCA], [https://pdbe.org/3wo4 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3wo4 RCSB], [https://www.ebi.ac.uk/pdbsum/3wo4 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3wo4 ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
[ | [https://www.uniprot.org/uniprot/IL18_HUMAN IL18_HUMAN] Augments natural killer cell activity in spleen cells and stimulates interferon gamma production in T-helper type I cells. | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
| Line 20: | Line 21: | ||
==See Also== | ==See Also== | ||
*[[Interleukin|Interleukin]] | *[[Interleukin 3D structures|Interleukin 3D structures]] | ||
*[[Interleukin receptor|Interleukin receptor]] | *[[Interleukin receptor 3D structures|Interleukin receptor 3D structures]] | ||
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Arita | [[Category: Homo sapiens]] | ||
[[Category: Ariyoshi | [[Category: Large Structures]] | ||
[[Category: Kato | [[Category: Arita K]] | ||
[[Category: Kimura | [[Category: Ariyoshi M]] | ||
[[Category: Kondo | [[Category: Kato Z]] | ||
[[Category: Ohnishi | [[Category: Kimura T]] | ||
[[Category: Shirakawa | [[Category: Kondo N]] | ||
[[Category: Tochio | [[Category: Ohnishi H]] | ||
[[Category: Tsutsumi | [[Category: Shirakawa M]] | ||
[[Category: Tochio H]] | |||
[[Category: Tsutsumi N]] | |||