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==Crystal structure of (R)-carbonyl reductase H49A mutant from Candida Parapsilosis in complex with 2-hydroxyacetophenone==
==Crystal structure of (R)-carbonyl reductase H49A mutant from Candida Parapsilosis in complex with 2-hydroxyacetophenone==
<StructureSection load='3wnq' size='340' side='right' caption='[[3wnq]], [[Resolution|resolution]] 2.95&Aring;' scene=''>
<StructureSection load='3wnq' size='340' side='right'caption='[[3wnq]], [[Resolution|resolution]] 2.95&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[3wnq]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3WNQ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3WNQ FirstGlance]. <br>
<table><tr><td colspan='2'>[[3wnq]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Candida_parapsilosis Candida parapsilosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3WNQ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3WNQ FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=HXT:2-HYDROXY-1-PHENYLETHANONE'>HXT</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.95&#8491;</td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Alcohol_dehydrogenase Alcohol dehydrogenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.1.1 1.1.1.1] </span></td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=HXT:2-HYDROXY-1-PHENYLETHANONE'>HXT</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3wnq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3wnq OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3wnq RCSB], [http://www.ebi.ac.uk/pdbsum/3wnq PDBsum]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3wnq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3wnq OCA], [https://pdbe.org/3wnq PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3wnq RCSB], [https://www.ebi.ac.uk/pdbsum/3wnq PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3wnq ProSAT]</span></td></tr>
</table>
</table>
== Function ==
[https://www.uniprot.org/uniprot/A1X808_CANPA A1X808_CANPA]
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
<div class="pdbe-citations 3wnq" style="background-color:#fffaf0;"></div>
==See Also==
*[[Carbonyl reductase 3D structures|Carbonyl reductase 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Alcohol dehydrogenase]]
[[Category: Candida parapsilosis]]
[[Category: Chan, H C]]
[[Category: Large Structures]]
[[Category: Guo, R T]]
[[Category: Chan HC]]
[[Category: Huang, C H]]
[[Category: Guo RT]]
[[Category: Ko, T P]]
[[Category: Huang CH]]
[[Category: Nie, Y]]
[[Category: Ko TP]]
[[Category: Wang, S S]]
[[Category: Nie Y]]
[[Category: Xiao, R]]
[[Category: Wang SS]]
[[Category: Xu, Y]]
[[Category: Xiao R]]
[[Category: Zhang, R Z]]
[[Category: Xu Y]]
[[Category: Carbonyl reductase]]
[[Category: Zhang RZ]]
[[Category: Oxidoreductase]]

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