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==The complex structure of TcSQS with ligand, E5700==
==The complex structure of TcSQS with ligand, E5700==
<StructureSection load='3wcc' size='340' side='right' caption='[[3wcc]], [[Resolution|resolution]] 2.32&Aring;' scene=''>
<StructureSection load='3wcc' size='340' side='right'caption='[[3wcc]], [[Resolution|resolution]] 2.32&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[3wcc]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3WCC OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3WCC FirstGlance]. <br>
<table><tr><td colspan='2'>[[3wcc]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Trypanosoma_cruzi_strain_CL_Brener Trypanosoma cruzi strain CL Brener]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3WCC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3WCC FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=E5S:(3R)-3-({2-BENZYL-6-[(3R,4S)-3-HYDROXY-4-METHOXYPYRROLIDIN-1-YL]PYRIDIN-3-YL}ETHYNYL)-1-AZABICYCLO[2.2.2]OCTAN-3-OL'>E5S</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.32&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3wca|3wca]], [[3wc9|3wc9]], [[3wcb|3wcb]], [[3wcd|3wcd]], [[3wce|3wce]], [[3wcf|3wcf]], [[3wcg|3wcg]], [[3wch|3wch]], [[3wci|3wci]], [[3wcj|3wcj]], [[3wcl|3wcl]], [[3wcm|3wcm]]</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=E5S:(3R)-3-({2-BENZYL-6-[(3R,4S)-3-HYDROXY-4-METHOXYPYRROLIDIN-1-YL]PYRIDIN-3-YL}ETHYNYL)-1-AZABICYCLO[2.2.2]OCTAN-3-OL'>E5S</scene></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Squalene_synthase Squalene synthase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.5.1.21 2.5.1.21] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3wcc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3wcc OCA], [https://pdbe.org/3wcc PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3wcc RCSB], [https://www.ebi.ac.uk/pdbsum/3wcc PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3wcc ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3wcc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3wcc OCA], [http://pdbe.org/3wcc PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3wcc RCSB], [http://www.ebi.ac.uk/pdbsum/3wcc PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3wcc ProSAT]</span></td></tr>
</table>
</table>
== Function ==
[https://www.uniprot.org/uniprot/Q4CWB4_TRYCC Q4CWB4_TRYCC]
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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</div>
</div>
<div class="pdbe-citations 3wcc" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 3wcc" style="background-color:#fffaf0;"></div>
==See Also==
*[[Squalene synthase|Squalene synthase]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Squalene synthase]]
[[Category: Large Structures]]
[[Category: Chan, H C]]
[[Category: Trypanosoma cruzi strain CL Brener]]
[[Category: Chen, C C]]
[[Category: Chan HC]]
[[Category: Guo, R T]]
[[Category: Chen CC]]
[[Category: Huang, C H]]
[[Category: Guo RT]]
[[Category: Ko, T P]]
[[Category: Huang CH]]
[[Category: Li, Q]]
[[Category: Ko TP]]
[[Category: Ren, F]]
[[Category: Li Q]]
[[Category: Shang, N]]
[[Category: Ren F]]
[[Category: Zheng, Y]]
[[Category: Shang N]]
[[Category: Zhu, Z]]
[[Category: Zheng Y]]
[[Category: Drug discovery]]
[[Category: Zhu Z]]
[[Category: E5700]]
[[Category: Isoprenoid]]
[[Category: Transferase]]
[[Category: Trypanosoma cruzi squalene synthase]]

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