3wc8: Difference between revisions

<table><tr><td colspan='2'>[[3wc8]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Equus_caballus Equus caballus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3WC8 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3WC8 FirstGlance]. <br>

</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=HEC:HEME+C'>HEC</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene>, <scene name='pdbligand=PG4:TETRAETHYLENE+GLYCOL'>PG4</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>

<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3nbs|3nbs]]</td></tr>

<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3wc8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3wc8 OCA], [http://pdbe.org/3wc8 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3wc8 RCSB], [http://www.ebi.ac.uk/pdbsum/3wc8 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3wc8 ProSAT]</span></td></tr>

[[http://www.uniprot.org/uniprot/CYC_HORSE CYC_HORSE]] Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain.  Plays a role in apoptosis. Suppression of the anti-apoptotic members or activation of the pro-apoptotic members of the Bcl-2 family leads to altered mitochondrial membrane permeability resulting in release of cytochrome c into the cytosol. Binding of cytochrome c to Apaf-1 triggers the activation of caspase-9, which then accelerates apoptosis by activating other caspases (By similarity).  

[[Category: Deshpande, M S]]

[[Category: Higuchi, Y]]

[[Category: Hirota, S]]

[[Category: Kamikubo, H]]

[[Category: Kataoka, M]]

[[Category: Komori, H]]

[[Category: Nagao, S]]

[[Category: Parui, P P]]

[[Category: Electron transport]]